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Dextrin-based hydrogel for the development of injectable bone substitute

Pereira, Isabel; Simões, J.; Fraga, S.; Maltez, L.; Evtuguin, D. V.; Domingues, R. M.; Coimbra, M. A.; Teixeira, J. P.; Maurício, A. C.; Santos, J. D.

[Excerpt] The development of injectable bone substitutes (IBS) have garnered great importance in the bone regeneration field, as a strategy to reach areas of the body using minimally invasive procedures, and showing the ability of perfect fitting according to irregularities of bone tissue defects. In this context, the combination of injectable hydrogels and ceramic granules is emerging as a well-established tre...


Evaluation of a starch-based double layer scaffold for bone regeneration in a r...

Requicha, J. F.; Moura, T.; Leonor, I. B.; Martins, T.; Muñoz, F.; Reis, R. L.; Gomes, M. E.; Viegas, Carlos A.

Damages in the maxillofacial bones are frequent in humans following trauma, metabolic diseases, neoplasia, or inflammatory processes. Many of the available treatments to regenerate bone are often ineffective. The goal of this work was to assess the in vivo behavior of an innovative double-layered scaffold based on a blend of starch and polycaprolactone (SPCL) that comprises a membrane obtained by solvent castin...


A tissue engineering approach for periodontal regeneration based on a biodegrad...

Requicha, J. F.; Viegas, C. A.; Muñoz, F.; Azevedo, J. M.; Leonor, I. B.; Reis, R. L.; Gomes, Manuela E.

Human and canine periodontium are often affected by an inflammatory pathology called periodontitis, which isassociated with severe damages across tissues, namely, in the periodontal ligament, cementum, and alveolarbone. However, the therapies used in the routine dental practice, often consisting in a combination of differenttechniques, do not allow to fully restore the functionality of the periodontium. Tissue ...


Los Rajiformes (Chondrichthyes, Batomorphii) del Plioceno inferior de la Formac...

Garcia, E.X.M.,; Balbino, A,; Antunes, M.T.; Muñoz, F.; Civis, J.

Se estudiaron los dientes de rayiformes provenientes de ocho localidades de la Formación Arenas de Huelva (Plioceno inferior), suroeste de la Cuenca del Guadalquivir, España. La formación inicia con un nivel de limos glauconíticos datado en 5,33 millones de años (González-Delgado et al. 2004), este nivel es rico en dientes de seláceos, suprayacente siguen una secuencia de arenas limosas con diferentes intercala...


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