3 documents found, page 1 of 1
TLR4 deletion increases basal energy expenditure and attenuates heart apoptosis...
de Vicente, Larissa G.; Muñoz, Vitor R.; Pinto, Ana P.; Rovina, Rafael L.; da Rocha, Alisson L.; Marafon, Bruno B.; Tavares, Maria Eduarda de A. [UNESP]Made available in DSpace on 2022-04-29T08:46:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-15; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Strategies capable of attenuating TLR4 can attenuate metabolic processes such as inflammation, endopla...
Long-term effects of moderate physical exercise during early childhood on insul...
Pereira, Rodrigo Martins; Muñoz, Vitor R.; Anaruma, Chadi P.; Gaspar, Rafael Calais; Gaspar, Rodrigo S.; Ropelle, Eduardo R.; Cintra, DennysIt is of great importance to investigate the effects of physical exercise for metabolic health when performed in early life, and what the adulthood response would be. The aim of this study is to analyse the effects of moderate intensity physical exercise protocol during childhood on the adipose tissue and insulin sensitivity of rats during adulthood. Twenty weaned Wistar (28 days old) were divided into control ...
Obesity increases mitogen-activated protein kinase phosphatase-3 levels in the ...
Rodrigues, Bárbara de A.; Muñoz, Vitor R.; Kuga, Gabriel K. [UNESP]; Gaspar, Rafael C.; Nakandakari, Susana C. B. R.; Crisol, Barbara M.Made available in DSpace on 2018-12-11T16:50:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-10-09; Mitogen-activated Protein Kinase Phosphatase 3 (MKP-3) has been involved in the negative regulation of insulin signaling. The absence of MKP-3 is also associated with reduced adiposity, increased energy expenditure and improved insulin sensitivity. The MKP-3 is known as the main Erk1/2 phosphatase and F...