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Frequency of Human Papillomavirus Detection in Chagasic Megaesophagus Associate...
Munari, Fernanda Franco; Sichero, Laura; Carloni, Adriana Cruvinel; Lacerda, Croider Franco; Nunes, Emily Montosa; De Oliveira, Antônio Talvane TorresMade available in DSpace on 2022-04-29T08:35:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Background: Chagasic megaesophagus (CM) as well as the presence of human papillomavirus (HPV) has been reported as etiological factors for esophageal squamous cell carcinoma (ESCC). Objective: We assessed the prevalence of HPV DNA in a series of ESCCs associated or not with CM. Data obtained were furthe...
Establishment, molecular and biological characterization of HCB-514: a novel hu...
Rosa, Marcela Nunes; Evangelista, Adriane Feijó; Leal, Letícia Ferro; De Oliveira, Cristina Mendes; Silva, Viviane Aline OliveiraCervical cancer is the fourth most common cancer in women. Although cure rates are high for early stage disease, clinical outcomes for advanced, metastatic, or recurrent disease remain poor. To change this panorama, a deeper understanding of cervical cancer biology and novel study models are needed. Immortalized human cancer cell lines such as HeLa constitute crucial scientific tools, but there are few other ce...
PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated ...
Munari, Fernanda Franco; Cruvinel-Carloni, Adriana; Lacerda, Croider Franco; De Oliveira, Antônio Talvane Torres; Scapulatempo-Neto, CristovamMade available in DSpace on 2019-10-06T16:11:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-12-29; Background: Chronic diseases such as chagasic megaesophagus (secondary to Chagas' disease) have been suggested as etiological factors for esophageal squamous cell carcinoma; however, the molecular mechanisms involved are poorly understood. Objective: We analyzed hotspot PIK3CA gene mutations in a series...
The relationship between esophageal cancer, chagasic megaesophagus and HPV: myt...
Munari, Fernanda Franco; Carloni, Adriana Cruvinel; Mariano, Vânia Sammartino; Syrjanen, Kari; Reis, R. M.; Longatto, AdhemarA supposed role for persistent high-risk human papillomavirus (HPV) infection in esophageal squamous cell carcinoma (ESCC) etiology has been suggested by a number of studies. Concomitantly, megaesophagus induced by the Trypanosoma cruzi cell-cycle activity also shows a potential association with ESCC. This review discusses esophageal cancer and the potential association between chagasic megaesophagus and HPV as...
PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated ...
Munari, Fernanda Franco; Cruvinel-Carloni, Adriana; Lacerda, Croider Franco; de Oliveira, Antônio Talvane Torres; Scapulatempo-Neto, CristovamChronic diseases such as chagasic megaesophagus (secondary to Chagas' disease) have been suggested as etiological factors for esophageal squamous cell carcinoma; however, the molecular mechanisms involved are poorly understood.