25 documents found, page 1 of 3
Moyamoya disease and syndrome: a review
Demartini Jr.,Zeferino; Teixeira,Bernardo CA.; Koppe,Gelson Luis; Gatto,Luana A. Maranha; Roman,Alex; Munhoz,Renato PuppiAbstract Moyamoya disease is a chronic occlusive cerebrovascular disease that is non-inflammatory and non-atherosclerotic. It is characterized by endothelial hyperplasia and fibrosis of the intracranial portion of the carotid artery and its proximal branches, leading to progressive stenosis and occlusion, often clinically manifesting as ischemic or hemorrhagic stroke with high rates of morbidity and mortality. ...
The Parkinson's disease and restless legs syndrome/Willis-Ekbom disorder link: ...
Munhoz,Renato Puppi; Constantino,Maria C. L.; Silveira-Moriyama,LauraABSTRACT Parkinson's disease (PD) and restless legs syndrome/Willis-Ekbom disorder (RLS/WED) are relatively common diseases in the realm of movement disorders. The fact that both may, as expected, co-occur and typically share a similar remarkable response to dopaminergic treatment raised the interest in exploration of additional shared features that throughout the years cruised fields as diverse as phenomenolog...
Édouard Brissaud: distinguished neurologist and Charcot’s pupil
Marques,Paula Teixeira; Germiniani,Francisco Manoel Branco; Camargo,Carlos Henrique Ferreira; Munhoz,Renato Puppi; Teive,Hélio Afonso GhizoniABSTRACT Professor Charcot had several pupils in his famous neurological service at the Salpêtrière Hospital in Paris, France. Among them, Édouard Brissaud was one of Charcot’s favorite pupils, temporarily becoming his successor after Charcot’s death. Brissaud’s neurological contributions were significant, including the description of hemifacial spasm, “geste antagoniste” in dystonia, pseudobulbar affect, post-...
Apomorphine in the treatment of Parkinson's disease: a review
Pessoa,Renata Ramina; Moro,Adriana; Munhoz,Renato Puppi; Teive,Hélio A.G.; Lees,Andrew J.ABSTRACT Optimizing idiopathic Parkinson's disease treatment is a challenging, multifaceted and continuous process with direct impact on patients’ quality of life. The basic tenet of this task entails tailored therapy, allowing for optimal motor function with the fewest adverse effects. Apomorphine, a dopamine agonist used as rescue therapy for patients with motor fluctuations, with potential positive effects o...
Treatment of hemifacial spasm with botulinum toxin type a: effective, long last...
Batisti,Jean Pierre Mette; Kleinfelder,Alais Daiane Fadini; Galli,Natália Bassalobre; Moro,Adriana; Munhoz,Renato Puppi; Teive,Hélio Afonso GhizoniABSTRACT Hemifacial spasm (HFS) is a common movement disorder characterized by involuntary tonic or clonic contractions of the muscles innervated by the facial nerve. Objective To evaluate the long-term effect of botulinum toxin type A (BTX-A) in the treatment of HFS. Methods A retrospective analysis of patients treated at the Movement Disorders Outpatient Clinic in the Neurology Service, Hospital de Clínicas, ...
Charcot’s famous secretaries
Teive,Hélio Afonso Ghizoni; Germiniani,Francisco Manoel Branco; Munhoz,Renato Puppi; Walusinski,OlivierABSTRACT At the pinnacle of his career, Professor Charcot had four secretaries: Charles Féré, Pierre Marie, Georges Gilles de la Tourette and Georges Guinon. They helped the great founder of neurology with his activities at La Salpêtrière Hospital and his private clinic, examining patients before he made the final diagnosis.
Cognitive dysfunction in corticobasal degeneration
Oliveira,Laís Machado de; Barcellos,Igor; Teive,Hélio A.G.; Munhoz,Renato PuppiABSTRACT Corticobasal degeneration (CBD) was originally described as a distinct clinicopathological entity in 1967. Since then, different phenotypic presentations have emerged as possible manifestations of CBD histopathological findings. In addition, pathophysiological findings and the molecular basis have been delineated and several aspects of its cognitive manifestations have been clarified. Thus, not only th...
Spinocerebellar ataxia type 10 in the South of Brazil: the Amerindian-Belgian c...
Teive,Hélio Afonso Ghizoni; Moro,Adriana; Moscovich,Mariana; Arruda,Walter Oleskho; Munhoz,Renato Puppi; Raskin,Salmo; Teive,Gladys Mary GhizoniSpinocerebellar ataxia type 10 (SCA10) is a rare form of autosomal dominant ataxia found predominantly in patients from Latin America with Amerindian ancestry. The authors report the history of SCA10 families from the south of Brazil (the states of Paraná and Santa Catarina), emphasizing the Belgian-Amerindian connection.
Cervical dystonia: about familial and sporadic cases in 88 patients
Camargo,Carlos Henrique F.; Camargos,Sarah Teixeira; Becker,Nilson; Munhoz,Renato Puppi; Raskin,Salmo; Cardoso,Francisco Eduardo C.Cervical dystonia (CD) affects the musculature of the neck in a focal way or associated to other parts of the body. The aim of this study was to identify clinical differences between patients with dystonia patients without family history and with family history (sporadic). Eighty-eight patients with CD were recruited in a Movement Disorders Clinic between June of 2008 and June of 2009. Only patients with no eti...
Edgar Allan Poe and neurology
Teive,Hélio Afonso Ghizoni; Paola,Luciano de; Munhoz,Renato PuppiEdgar Allan Poe was one of the most celebrated writers of all time. He published several masterpieces, some of which include references to neurological diseases. Poe suffered from recurrent depression, suggesting a bipolar disorder, as well as alcohol and drug abuse, which in fact led to his death from complications related to alcoholism. Various hypotheses were put forward, including Wernicke's encephalopathy.