7 documents found, page 1 of 1
Membrane trafficking alterations in breast cancer progression
Ferreira, Andreia; Castanheira, Pedro; Escrevente, Cristina; C. Barral, Duarte; Barona, TeresaPublisher Copyright: Copyright © 2024 Ferreira, Castanheira, Escrevente, Barral and Barona.; Breast cancer (BC) is the most common type of cancer in women, and remains one of the major causes of death in women worldwide. It is now well established that alterations in membrane trafficking are implicated in BC progression. Indeed, membrane trafficking pathways regulate BC cell proliferation, migration, invasion, ...
RAB3A Regulates Melanin Exocytosis and Transfer Induced by Keratinocyte-Conditi...
Cabaço, Luís C.; Bento-lopes, Liliana; Neto, Matilde V.; Ferreira, Andreia; Staubli, Wanja B.l.; Ramalho, José S.; C Seabra, Miguel; C. Barral, DuarteFunding: We would like to thank our group for the critical reading of the manuscript and the NMS microscopy and cell culture facilities, as well as José Belo’s group, for the kind gift of mouse embryonic fibroblasts. This study was supported by Fundação para a Ciência e a Tecnologia (Portugal) through grant PTDC/BIA-CEL/29765/2017 and PhD fellowships to LCC, MVN, LBL and AF (2020.08812.BD, PD/BD/137442/2018, SF...
Liposomal Formulations of a New Zinc(II) Complex Exhibiting High Therapeutic Po...
Ribeiro, Nádia; Albino, Melissa; Ferreira, Andreia; Escrevente, Cristina; C. Barral, Duarte; Pessoa, João Costa; Reis, Catarina PintoFunding: The authors thank the financial support from Fundação para a Ciência e Tecnologia (FCT) through projects UIDB/00100/2020, UIDP/00100/2020, UIDB/04138/2020, UIDP/04138/2020, LA/P/0056/2020, and PTDC/QUI-QIN/0586/2020. N. Ribeiro acknowledges FCT for the SFRH/BD/ 135797/2018 grant. Andreia Ferreira acknowledges FCT for the PD/BD/135506/2018 grant.; Colorectal cancer is the second leading cause of cancer-...
Development of Dl1.72, a novel anti-DLL1 antibody with anti-tumor efficacy agai...
Silva, Gabriela; Sales-Dias, Joana; Casal, Diogo B.; Alves, Sara; Domenici, Giacomo; Barreto, Clara; Matos, Carolina; Lemos, Ana R.; Matias, Ana T.Funding Information: Funding: This research was funded by Fundação para a Ciência e Tecnologia, Portugal, grants PTDC/BBB-BMD/4497/2014 (to A.B.) and PD/BD/113987/2015 (to J.S.-D.), iBETXplore grants 3D-ABC-PI-717 (to G.D.) and BiACaT-HER2:JAG1 (to G.S.). iNOVA4Health—UIDB/04462/2020 and UIDP/04462/2020, a program financially supported by Fundação para a Ciência e Tecnolo-gia/Ministério da Ciência, Tecnologia e...
The Role of ARF Family Proteins and Their Regulators and Effectors in Cancer Pr...
Casalou, Cristina; Ferreira, Andreia; C. Barral, DuarteAF was funded by a Ph.D. fellowship (PD/BD/135506/2018) from the Fundação para a Ciência e a Tecnologia (FCT) and DB by the FCT Investigator Program (IF/00501/2014/CP1252/CT0001).; The Adenosine diphosphate-Ribosylation Factor (ARF) family belongs to the RAS superfamily of small GTPases and is involved in a wide variety of physiological processes, such as cell proliferation, motility and differentiation by regu...
The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells
Sales-Dias, Joana; Silva, Gabriela; Lamy, Márcia; Ferreira, Andreia; Barbas, AnaBreast cancer (BC) is the most common type of cancer in women and has a high rate of relapse and death. Notch signaling is crucial for normal breast development and homeostasis. Dysregulation of Notch receptors and ligands has been detected in different BC subtypes and shown to be implicated in tumor development, progression, drug resistance, and recurrence. However, the effects of Notch ligands in various type...
Arl13b regulates breast cancer cell migration and invasion by controlling integ...
Casalou, Cristina; Faustino, Alexandra; Silva, Fernanda; Ferreira, Inês C.; Vaqueirinho, Daniela; Ferreira, Andreia; Castanheira, Pedro; Barona, TeresaThis work was supported by PhD fellowships from Fundação para a Ciência e a Tecnologia(FCT) to A. Faustino, A. Ferreira and P.C. (PD/BD/105898/2014, PD/BD/135506/2018 and PD/BD/128339/2017, respectively), a post-doctoral fellowship from FCT to C.C. (SFRH/BPD/78561/2011), the FCT Investigator Program to D.C.B. (IF/00501/2014/CP1252/CT0001), and grants from FCT (PTDC/BIM-MEC/4905/2014) and iNOVA4Health - UID/Mult...