5 documents found, page 1 of 1
Migraine in 746 patients with multiple sclerosis
Fragoso,Yara Dadalti; Adoni,Tarso; Alves-Leon,Soniza V.; Apostolos-Pereira,Samira L.; Carneiro,Marcos A. Diniz; Chikota,Edila M.ABSTRACT Migraine adds to the burden of patients suffering from multiple sclerosis (MS). The ID-migraine is a useful tool for screening migraine, and the Migraine Disability Assessment questionnaire can evaluate disease burden. The aim of the present study was to assess the presence and burden of migraine in patients with MS. Methods: Patients diagnosed with MS attending specialized MS units were invited to ans...
Serological profile of John Cunningham virus (JCV) in patients with multiple sc...
Branco,Luciana Prats; Adoni,Tarso; Apostolos-Pereira,Samira Luisa; Brooks,Joseph Bruno Bidin; Correa,Eber Castro; Damasceno,Carlos AugustoABSTRACT Treatment options for multiple sclerosis (MS) have changed over the last few years, bringing about a new category of drugs with more efficient profiles. However, these drugs have come with a whole new profile of potential adverse events that neurologists have to learn well and quickly. One of the most feared complications of these MS treatments is progressive multifocal leukoencephalopathy caused by th...
Natalizumab adverse events are rare in patients with multiple sclerosis
Fragoso,Yára Dadalti; Alves-Leon,Soniza Vieira; Arruda,Walter Oleschko; Carvalho,Margarete de Jesus; Comini-Frota,Elizabeth Regina; Corrêa,Éber CastroObjective To assess the prevalence and the profile of adverse events (AE) of natalizumab in patients with multiple sclerosis (MS). Methods Data collection from neurologists attending to patients with MS at specialized units in Brazil. Results Data from 103 patients attending the infusion centers of 16 MS units in 9 Brazilian states were included in the study. The total number of infusions was 1,042. Seventy-nin...
Nearly one-half of Brazilian patients with multiple sclerosis using natalizumab...
Fragoso,Yara Dadalti; Mendes,Maria Fernanda; Arruda,Walter Oleschko; Becker,Jefferson; Brooks,Joseph Bruno Bidin; Carvalho,Margarete de JesusObjective Natalizumab is a new and efficient treatment for multiple sclerosis (MS). The risk of developing progressive multifocal leukoencephalopathy (PML) during the use of this drug has created the need for better comprehension of JC virus (JCV) infection. The objective of the present study was to assess the prevalence of JCV-DNA in Brazilian patients using natalizumab. Method Qualitative detection of the JCV...
Urodynamic features of the voiding dysfunction in HTLV-1 infected individuals
Castro,Neviton M.; Freitas,Daniel M.; Rodrigues Jr.,Waldyr; Muniz,Andre; Oliveira,Paulo; Carvalho,Edgar M.OBJECTIVE:To describe urodynamic abnormalities in HTLV-1 infected individuals presenting urinary symptoms and verify if these findings and quality of life (QOL) evaluation correlate with overall neurological impairment. MATERIALS AND METHODS: From January/2001 to May/2004, 324 HTLV-1 seropositive subjects were evaluated to determine the occurrence of urinary symptoms. Urodynamic testing was performed in those w...