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Efficient delivery of DNA into bovine preimplantation embryos by multiwall carb...

Munk, Michele; Ladeira, Luiz Orlando; Carvalho, Bruno Campos de; Raposo, Nádia Rezende Barbosa; Serapião, Raquel V.; Quintão, Carolina Capobiango Romano

The pellucid zone (PZ) is a protective embryonic cells barrier against chemical, physical or biological substances. This put, usual transfection methods are not efficient for mammal oocytes and embryos as they are exclusively for somatic cells. Carbon nanotubes have emerged as a new method for gene delivery, and they can be an alternative for embryos transfection, however its ability to cross the PZ and mediate...

Date: 2018   |   Origin: Oasisbr
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