6 documents found, page 1 of 1
Morphologic Patterns and Treatment of Transplant Glomerulopathy: a Retrospectiv...
Abreu, R; Carvalho, F; Viana, H; Mesquita, I; Possante, M; Aires, I; Caeiro, F; Silva, C; Cotovio, P; Ferreira, A; Remédio, F; Nolasco, FTransplant glomerulopathy is mainly due to chronic antibody-mediated rejection and actually represents a major cause of long-term allograft failure. The lack of effective treatment remains a serious problem in transplantation. A retrospective and uni-center study was performed in 48 kidney allograft recipients with transplant glomerulopathy between January 2010 and December 2015. Median time for diagnosis was 7...
A Rare Malignancy in the Post -Transplant Period: Myeloma Cast Nephropathy
Mesquita, I; Viana, H; Possante, M; João, C; Carvalho, S; Silva, C; Aires, I; Ferreira, A; Remédio, F; Carvalho, F; Nolasco, FMyeloma-associated renal disorders are rare events among renal transplants and can occur as recurrent or de novo disease. We describe an unusual case of renal allograft dysfunction due to myeloma cast nephropathy occurring 19 years after having received a renal transplant in a patient with no prior history of multiple myeloma or monoclonal gammopathy preceding transplantation. Our patient was treated with five ...
Leflunomide and Polyomavirus-Associated Nephropathy in Renal Transplant
Ferreira, AC; Ferreira, A; Possante, M; Sousa, J; Viana, H; Carvalho, H; Nolasco, FPolyomavirus nephropathy is a major complication in renal transplantation, associated with renal allograft loss in 14 to 80% of cases. There is no established treatment, although improvement has been reported with a variety of approaches. The authors report two cases of polyomavirus infection in renal allograft recipients. In the first case, a stable patient presented with deterioration of renal function, worse...
Sirolimus-Induced Drug Fever in a Renal Transplant Patient: a Case Report
Aires, I; Carvalho, D; Remédio, F; Possante, M; Ferreira, A; Pinto, JR; Nolasco, F; Ribeiro Santos, JHerein we have described the case of a male renal transplant recipient who developed drug fever apparently related to sirolimus. He had been stable under an immunosuppressive regimen of tacrolimus and mycophenolate mofetil, but developed acute cellular rejection at 5 years after transplantation due to noncompliance. Renal biopsy showed marked interstitial fibrosis, and immunosuppression was switched from mycoph...
Leukopenia in Kidney Transplant Patients with the Association of Valganciclovir...
Brum, S; Nolasco, F; Sousa, J; Ferreira, A; Possante, M; Pinto, JR; Barroso, E; Ribeiro Santos, JCytomegalovirus (CMV) is the most common viral infection after transplantation. Valganciclovir (VGC) is established for prophylaxis and treatment of CMV infections, but leukopenia which appears in 10% to 13% (severe in 4.9%) is the principal side effect. We have recently noted an increased incidence of leukopenia and severe neutropenia among our renal transplant patients and thought to identify the associated f...
Triple Regimen with Rituximab, Plasmapheresis and Intravenous Immunoglobulin in...
Pessegueiro, P; Nolasco, F; Sampaio, S; Carvalho, F; Manuel, F; Barber, E; Viana, H; Sousa, J; Possante, M; Domingos, M; Reimão Pinto, JIntroduction: The clinical importance of humoral-mediated acute rejection has been progressively recognised. Early recognition and treatment with plasmapheresis and intravenous immunoglobulin have recently improved short term prognosis. Case report: In this report we describe the clinical features of three 2nd transplant patients developing severe acute humoral rejection during the first week post-transplant wh...