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Old and new calcimimetics for treatment of secondary hyperparathyroidism: Impac...

Pereira, L; Meng, C; Marques, D; Frazão, JM

Secondary hyperparathyroidism (SHPT) is associated with increased bone turnover, risk of fractures, vascular calcifications, and cardiovascular and all-cause mortality. The classical treatment for SHPT includes active vitamin D compounds and phosphate binders. However, achieving the optimal laboratory targets is often difficult because vitamin D sterols suppress parathyroid hormone (PTH) secretion, while also p...


Reactivation of Hepatitis B virus in kidney transplant recipients with previous...

Meng, C; Belino, C; Pereira, L; Pinho, A; Sampaio, S; Tavares, I; Bustorff, M; Sarmento, A; Manuel, P

Background: Hepatitis B virus (HBV) reactivation in kidney transplant recipients (KTR) involves important morbidity and mortality. Despite being more common in patients who are HBsAg-positive, it may occur in patients with clinically resolved infection (HBsAg-negative and anti-HBc-positive), in whom the presence of the protective anti-HB antibody is thought to decrease the risk of reactivation. Data regarding r...


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