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Bioactivity of honey: phenolic composition, antioxidant trends and carcinoma ce...

Mutlu, Ceren; Demir, Zeynep; Aylanc, Volkan; Özkan, Aysun; Erbaş, Mustafa

Honey is not only a food source but also a valuable substance for health and medicine, owing to its complex composition and bioactive properties. However, there is very limited information on the changes in the active compounds of honey during digestion and their antioxidant capacity and effect on cancer cells at the end of digestion. Herein, we investigate the dynamic changes in their bioactive compound compos...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Fatty acids profile in the honeybee: metabolic pathways, stressor interactions,...

Mutlu, Ceren; Vilas-Boas, Miguel

Fatty acids play a crucial role in the metabolic activities, health, cognitive development, and behaviors of honeybees. The primary source of fatty acids for honeybees is the pollen consumed, though they can also produce specific fatty acids through de novo synthesis. Among the saturated fatty acids in honeybees, palmitic and stearic acids are the most abundant, while common unsaturated fatty acids include olei...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Safflower Protein Hydrolysates: Physicochemical, Functional Properties and Anti...

Korkmaz, Fatma; Mutlu, Ceren

This study aimed to investigate the effect of enzymatic hydrolysis on the physicochemical, functional, and antioxidant properties of safflower protein isolate and hydrolysates. Isolated safflower protein was hydrolyzed by both Alcalase and Flavourzyme at the degree of hydrolysis of 2%, 4%, 6%, 8%, and 10%. Safflower protein hydrolysates exhibited a lighter color (3.74%–8.79%) and reduced redness (69.11%–102.85%...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Bee Pollen as a Dietary Mineral Source: In Vitro Bioaccessibility and Health Ri...

Mutlu, Ceren; Aylanc, Volkan; Vilas-Boas, Miguel

Pollen, the male gametophyte of flowering plants, is collected by honeybees as a primary source of protein and converted into bee pollen through the enzymatic activity of digestive secretions. The nutrients in bee pollen are available in amounts well beyond those of proteins, comprising macronutrients such as carbohydrates, lipids and dietary fiber, as well as micronutrients such as minerals, vitamins, organic ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Phenolic changes in propolis during in vitro digestion and cytotoxic effects on...

Mutlu, Ceren; Demir, Zeynep; Özkan, Aysun; Erbaş, Mustafa

This study aimed to evaluate the compositional changes and bioaccessibility of phenolics and antioxidants in propolis during in vitro digestion as well as the cytotoxic effects of digested propolis on various cancer cell lines. Design/methodology/approach – Six propolis samples were obtained and subjected to in vitro oral, gastric and intestinal digestion. Both digested and undigested samples were analyzed for ...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Optimisation of Catalytic Oxidation Conditions for the 2‐Keto‐L‐Gulonic Acid Pr...

Mutlu, Ceren; Candal‐Uslu, Cihadiye; Erbaş, Mustafa

L-Ascorbic acid, also known as vitamin C, is a very important antioxidant ingredient situated many usage areas in different industries. 2-keto-L-gulonic acid (2-KLG) is the main precursor component of L-ascorbic acid production and it can be produced from L-sorbose via microbial fermentation or chemical (catalytic) oxidation. While some special strains are used in microbial fermentation, it is benefitted from s...

Date: 2024   |   Origin: Biblioteca Digital do IPB

Bee bread: sorption isotherms, thermodynamic characteristics of moisture adsorp...

Mutlu, Ceren

Bee bread is a value-added apiculture product produced from bee pollen by mixed lactic acid fermentation. Although many studies focused on the bioactive components and health effects of the bee bread, there is no study concerned with understanding its moisture adsorption properties. Herein, it was aimed to evaluate moisture adsorption properties and thermodynamics of bee bread using different sorption models at...

Date: 2024   |   Origin: Biblioteca Digital do IPB

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