Coxiella burnetii, the causative agent of Q fever, is a globally distributed zoonosis, with cattle, sheep, and goats considered the main reservoirs of the disease (Agger et al,., 2013; Bento et al., 2023). Human transmission primarily occurs through inhaling infections aerosols from milk, faeces, urina, and birth products from infected ruminants. This study used a 2-year longitudinal approach to investigate C. ...
Infectious feline upper respiratory tract disease is very common and Aelurostrongylus abstrusus is the most often diagnosed parasitic cause, although clinical signs may go unnoticed and diagnosis is challenging as it has several limitations. Noting that more cases have been recorded in recent years, the authors, in the present work, describe in detail the features of five cases of Aelurostrongylus abstrusus reg...
Hair follicular tumours in dog comprise a large and heterogeneous group of neoplasms that display morphological features resembling one or several portions of the normal hair follicle which constitute a huge effort for its diagnosis. Histopathological evaluation is required to better characterize the different types of canine hair follicular tumours, in order to better understand its biological behaviour and to...
During compound screening and drug development, long-term oral drug administration to experimental rodents is often required. Oral gavage, a straightforward drug dosing technique, is not suitable for extended treatments considering the recurrent traumatic complications (gastroesophageal injury) and physiological distress (corticosterone levels alterations) that frequently bias experimental design outcomes. Thes...
A pele é o principal local de aparecimento de neoplasias no cão, e o segundo no gato (Scott et al., 2001). Sendo o maior órgão do corpo e sendo também facilmente observado, é natural que quaisquer alterações que aí surjam sejam mais facilmente detectadas, aumentando as possibilidades de um diagnóstico precoce e um melhor prognóstico Pretende-se alertar o Enfermeiro Veterinário para as principais neoplasias cutâ...
Introduction Ovine respiratory disease is frequently associated to high economic losses. It can be caused by several aetiological agents, difficulting the diagnosis and the implementation of effective therapeutic measures. The pathologist has a difficult, but very important role, in the diagnostic procedure, based on standard histomorphological classification of lung injury. Objectives The authors describe and ...
Objective: The high prevalence of chronic kidney disease underscores the failure to provide therapies to effectively halt, prevent, and/or reverse renal fibrosis. Thus, the aim of this study was to evaluate the effect of chronic treatment with chaethomellic acid A (CA) on renal fibrosis associated to 5/6 nephrectomy. Methods: Male Wistar rats were subjected to 5/6 nephrectomy (RMR) or sham-operated (SO). One we...
Introduction Neoplasms involving the optic nerve are rare. Intraorbital meningiomas, the most common tumour of the optic nerve, represent only 3% of all meningiomas in dogs, so few data exists to predict its symptoms and biologic behaviour. Objectives The authors describe and submit for discussion, a rare case of retrobulbar meningioma, in particular for assessment of histological grade and prognosis. Medical H...
Gastric Dilatation is a potentially fatal gastrointestinal pathology caused by aerophagy. It is mainly caused by rapid consumption of food, excitation or exercising near the time of feeding, which promotes the entrance of air into the stomach (Robbins et al, 2011). With this work we aim to emphasize the care given by veterinary nurses in this pathology.
Background: Apoptosis detection methods have been proposed for diagnostic purposes, in particular for determining the biological characteristics of tumours and, indirectly, their prognosis. Implementation of a new technique requires the use of an effective positive control for correct assessment. Most specialty publications on the subject, do not indicate the positive controls used and do not disclose the obtai...