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Associação entre o índice de anisocitose (RDW) e a ocorrência de morte ou enfar...

Nabais, Sérgio; Losa, Nuno; Gaspar, António; Rocha, Sérgia; Costa, João; Azevedo, Pedro; Basto, Luís; Pereira, Miguel Alvares; Correia, Adelino

Higher values of red ceildistribution width (RDW) may be associated with adverse outcomes in patients with heart failure and in those with stable coronary artery disease. We assessed the hypothesis that higher RDW values are associated with adverse cardiovascular outcomes in patients with acute coronary syndromes (ACS). BACKGROUND: Higher values of red ceildistribution width (RDW) may be associated with adverse...


Coexistence of coronary cameral fistulae and cor triatriatum sinister in an eld...

Nabais, Sérgio; Salomé, Nuno; Brandão, Aida; Simões, Alda; Marques, Jorge; Costa, João; Basto, Luís; Costeira, António; Correia, Adelino

Coronary cameral fistulae are unusual congenital or acquired anomalous communications between an epicardial coronary artery and a cardiac chamber. There are no reported cases of the association of coronary cameral fistulae and cor triatriatum, a rare congenital cardiac anomaly in which a fibromuscular membrane divides the left atrium into two chambers. We report the case of an 82-year-old man presenting with re...


Takayasu’s arteritis: time for new imaging techniques

Nabais, Sérgio; Gouveia, Paula; Barracha, Ivone; Lima, Maria João; Rodrigues Dias, António; Rua, Abel

Takayasu’s arteritis is a chronic, inflammatory and stenotic disease of unknown aetiology, involving medium- and large-sized arteries, primarily the aorta and its major branches and occasionally the pulmonary artery.The authors present the case of a 27-year-old woman with hypertension, referred to our Internal Medicine Department. Extensive vascular calcification in the large abdominal arteries, including the r...


E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations c...

Oliveira, Carla; Ferreira, Paulo; Nabais, Sérgio; Campos, Luísa; Ferreira, Ana; Cirnes, Luís; Alves, Catarina Castro; Veiga, Isabel; Fragoso, Maria

Approximately 30% of all hereditary diffuse gastric cancer (HDGC) families carry CDH1 germline mutations. The other two thirds remain genetically unexplained and are probably caused by alterations in other genes. Using polymerase chain reaction (PCR)/single-strand conformation polymorphism (SSCP)/sequencing, we screened 32 Portuguese families with a history of gastric cancer and 23 patients with early onset gas...


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