Encontrados 8 documentos, a visualizar página 1 de 1
Rasmussen Encephalitis: longterm outcome after surgery
Terra,Vera C.; Machado,Helio R.; Oliveira,Ricardo dos Santos; Serafini,Luciano N; Souza-Oliveira,Cecília; Escorsi-Rosset,SaraBACKGROUND AND PURPOSE: Rasmussen Encephalitis (RE) is characterized by intractable epilepsy, progressive hemiparesis and unilateral hemispheric atrophy. The progression of the symptoms usually occurs within months to few years. Antiepileptic drugs are usually not effective to control disease progression and epilepsy surgery in the form of hemispheric disconnection has been considered the treatment of choice. T...
The pilocarpine model of epilepsy: what have we learned?
Scorza,Fulvio A.; Arida,Ricardo M.; Naffah-Mazzacoratti,Maria da Graça; Scerni,Débora A.; Calderazzo,Lineu; Cavalheiro,Esper A.The systemic administration of a potent muscarinic agonist pilocarpine in rats promotes sequential behavioral and electrographic changes that can be divided into 3 distinct periods: (a) an acute period that built up progressively into a limbic status epilepticus and that lasts 24 h, (b) a silent period with a progressive normalization of EEG and behavior which varies from 4 to 44 days, and (c) a chronic period ...
Nestin down-regulation of cortical radial glia is delayed in rats submitted to ...
Scorza,Carla Alessandra; Arida,Ricardo Mario; Scorza,Fulvio Alexandre; Cavalheiro,Esper Abrão; Naffah-Mazzacoratti,Maria da GraçaOBJECTIVE: Nestin is temporarily expressed in several tissues during development and it is replaced by other protein types during cell differentiation process. This unique property allows distinguishing between undifferentiated and differentiated cells. This study was delineated to analyze the temporal pattern of nestin expression in cortical radial glial cells of rats during normal development and of rats subm...
Neurogenesis induced by seizures in the dentate gyrus is not related to mossy f...
Sanabria,Yaima del Carmen Garrido; Argañaraz,Gustavo Adolfo; Lima,Eliangela; Priel,Margareth Rose; Trindade,Edvaldo da Silva; Loeb,Luana MazzacorattiNeurogenesis in the dentate gyrus (DG) has attracted attention since abnormal supragranular mossy fiber sprouting occurs in the same region, in temporal lobe epilepsy. Thus, we submitted developing rats to pilocarpine-induced status epilepticus (SE) to study the relationship between neurogenesis and mossy fiber sprouting. Groups were submitted to SE at: I-P9, II-P7, P8 and P9, III-P17 e IV-P21. Neurogenesis was...
Estudo comparativo entre enxerto autógeno e enxerto muscular coberto com tubo d...
Fernandes,Marcela; Valente,Sandra Gomes; Amado,Débora; Fernandes,Maria José da Silva; Naffah-Mazzacoratti,Maria da Graça; Santos,João Baptista Gomes dosEste trabalho teve como objetivo o estudo da regeneração nervosa através da contagem de neurônios comparando duas técnicas cirúrgicas no tratamento da perda de substância nervosa nos membros inferiores em 15 ratos. Inicialmente obteve-se tubo de veia de 12mm de comprimento retirado da jugular externa esquerda. A seguir, opera-se os dois membros inferiores, expondo o nervo tibial de cada lado e ressecando um seg...
Efeito neuroprotetor da melatonina e N-acetilserotonina na epileptogênese e no ...
Lima,Eliângela de; Cabral,Francisco Romero; Cavalheiro,Esper Abrão; Naffah-Mazzacoratti,Maria da Graça; Amado,DéboraPURPOSE: The aim of this research was to study the effects of treatment with melatonin and N-acetilserotonin in the development of pilocarpina model of epilepsy in adult male rats. METHODS: Part I - The animals were divided in 4 groups: SALINE - animals that received only saline; SE - animals submitted to status epilepticus (SE); NAS + SE - animals that received pre-treatment with N-acetylserotonin and were sub...
Effect of glycemic state in rats submitted to status epilepticus during develop...
Santiago,Joselita F.C.; Carvalho,Fatima F.; Perosa,Sandra R.; Siliano,Marcelo R.; Cruz,José Walber M.C.; Fernandes,Maria José S.; Cavalheiro,Esper A.The effect of glycemic state on status epilepticus (SE) development was studied in animals of different ages, submitted to pilocarpine model of epilepsy. Groups: I- Rats with 9-day-old (P9): IA. Submitted to 1SE; IB. Saline-treated; IC. Induced- hyperglycemia; ID. Induced- hyperglycemia+SE; II- Rats submitted to three consecutive episodes of SE at P7, P8 and P9; III- Rats submitted to 1SE at P17; IV- Rats submi...
Monoamine responses to acute and chronic aerobic exercise in normotensive and h...
Arida,Ricardo Mario; Naffah-Mazzacoratti,Maria da Graça; Soares,Jesus; Cavalheiro,Esper AbrãoOBJECTIVES: The purpose of the present study was to compare the plasma and serum monoamine levels in sedentary, untrained normotensive and hypertensive men at rest with levels measured after an acute bout of exercise and to compare similar measurements following a 12-week aerobic training program. PLACE OF STUDY: The data obtained for this study was collected from a clinic for the prevention of heart disease an...