3 documents found, page 1 of 1
Acute physical exercise increases leptin-induced hypothalamic extracellular sig...
Gaspar, Rafael Calais, 1992-; Muñoz, Vitor Rosetto, 1993-; Nakandakari, Susana Castelo Branco Ramos; Minuzzi, Luciele Guerra; Botezelli, José DiegoAgradecimentos: The authors thank Obesity and Comorbidities Research Center – OCRC and FAPESP (2016/18488-8) and CNPq (306535/2017-3) for all support during the experiment; The obesity is a result of energy imbalance and the increase in thermogenesis seems an interesting alternative for the treatment of this disease. The mechanism of energy expenditure through thermogenesis is tightly articulated in the hypotha...
Impaired insulin signaling and spatial learning in middle-aged rats: The role o...
Kuga, Gabriel Keine [UNESP]; Muñoz, Vitor Rosetto; Gaspar, Rafael Calais; Nakandakari, Susana Castelo Branco Ramos; da Silva, Adelino Sanchez RamosMade available in DSpace on 2018-12-11T16:51:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-04-01; The insulin and Brain-Derived Neurotrophic Factor (BDNF) signaling in the hippocampus promotes synaptic plasticity and memory formation. On the other hand, aging is related to the cognitive decline and is the main risk factor for Alzheimer's Disease (AD). The Protein-Tyrosine Phosphatase 1B (PTP1B) is r...
Acute physical exercise increases the adaptor protein APPL1 in the hypothalamus...
Gaspar, Rafael Calais; Muñoz, Vitor Rosetto; Formigari, Guilherme Pedron; Kuga, Gabriel Keine [UNESP]; Nakandakari, Susana Castelo Branco RamosMade available in DSpace on 2018-12-11T16:53:06Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-10-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Adiponectin is considered an adipokine that has essential anti-inflammatory and insulin-sensitivity actions. The adaptor protein containing the pleckstrin homology domain,...