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The association of premorbid conditions with 6-month mortality in acutely admit...

de Lange, Dylan W; Soliman, Ivo W; Leaver, Susannah; Boumendil, Ariane; Haas, Lenneke E M; Watson, Ximena; Boulanger, Carol; Szczeklik, Wojciech

© 2024. The Author(s).; BACKGROUND: Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on 6 month survival. METHODS: Prospective cohort study in 242 ICUs from 22 countries including patients 80 years or above, admitted over a 6 months period to an ICU betwee...


Consent is a confounding factor in a prospective observational study of critica...

Flaatten, Hans; Guidet, Bertrand; Jung, Christian; Boumendil, Ariane; Leaver, Susannah; Szczeklik, Wojciech; Artigas, Antonio; Andersen, Finn

During analysis of a prospective multinational observation study of critically ill patients ≥80 years of age, the VIP2 study, we also studied the effects of differences in country consent for study inclusion. This is a post hoc analysis where the ICUs were analyzed according to requirement for study consent. Group A: ICUs in countries with no requirement for consent at admission but with deferred consent in sur...


Reliability of the Clinical Frailty Scale in very elderly ICU patients

Flaatten, Hans; Guidet, Bertrand; Andersen, Finn H; Artigas, Antonio; Cecconi, Maurizio; Boumendil, Ariane; Elhadi, Muhammed; Fjølner, Jesper

PURPOSE: Frailty is a valuable predictor for outcome in elderly ICU patients, and has been suggested to be used in various decision-making processes prior to and during an ICU admission. There are many instruments developed to assess frailty, but few of them can be used in emergency situations. In this setting the clinical frailty scale (CFS) is frequently used. The present study is a sub-study within a larger ...


Management and outcomes in critically ill nonagenarian versus octogenarian pati...

Bruno, Raphael Romano; Wernly, Bernhard; Kelm, Malte; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn H.; Artigas, Antonio; Finazzi, Stefano

Funding Information: This study was endorsed by the ESICM. Free support for running the electronic database and was granted from the dep. of Epidemiology, University of Aarhus, Denmark. Financial support for creation of the e-CRF and maintenance of the database was possible from a grant (open project support) by Western Health region in Norway) 2018 who also funded the participating Norwegian ICUs. DRC Ile de F...


Publisher Correction

Wernly, Bernhard; Bruno, Raphael Romano; Kelm, Malte; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn H.; Artigas, Antonio; Finazzi, Stefano

In the original version of this Article, the VIP2 Study Group was incorrectly listed as an author in the author list. All members of the VIP2 Study Group are listed in the accompanying Supplementary Information file. The error has been corrected in the PDF and HTML versions of the Article, and in the Supplementary Information files.


Sex-specific outcome disparities in very old patients admitted to intensive car...

Wernly, Bernhard; Bruno, Raphael Romano; Kelm, Malte; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn H; Artigas, Antonio; Finazzi, Stefano

Female and male very elderly intensive patients (VIPs) might differ in characteristics and outcomes. We aimed to compare female versus male VIPs in a large, multinational collective of VIPs with regards to outcome and predictors of mortality. In total, 7555 patients were included in this analysis, 3973 (53%) male and 3582 (47%) female patients. The primary endpoint was 30-day-mortality. Baseline characteristics...


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