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Genetic diversity of candidate loci linked to Mycobacterium tuberculosis resist...

Gómez-González, Paula J.; Perdigão, João; Gomes, Pedro; Puyen, Zully M.; Santos-Lazaro, David; Napier, Gary; Hibberd, Martin L.; Viveiros, Miguel

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the deadliest infectious diseases worldwide. Multidrug and extensively drug-resistant strains are making disease control difficult, and exhausting treatment options. New anti-TB drugs bedaquiline (BDQ), delamanid (DLM) and pretomanid (PTM) have been approved for the treatment of multi-drug resistant TB, but there is increasing resistance to them...

Date: 2021   |   Origin: Repositório da Universidade de Lisboa
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