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Immunotherapy, immunochemotherapy and chemotherapy for American cutaneous leish...

Mayrink, Wilson; Botelho, Ana Cristina de Carvalho; Magalhães, Paulo Araújo; Batista, Sebastião Mariano; Lima, Antonio de Oliveira; Genaro, Odair

O tratamento de primeira escolha para leishmaniose tegumentar americana é o antimonial pentavalente. Embora este tratamento seja na maioria das vezes efetivo e indicado, devem ser consideradas as desvantagens tais como efeitos colaterais, longa duração do tratamento e contra-indicação para cardiopatas, nefropatas, idosos, grávidas e outras condições. Com o advento da vacina antileishmaniose tegumentar americana...

Date: 2014   |   Origin: Oasisbr
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Antigenicity of a whole parasite vaccine as promising candidate against canine ...

Giunchetti, Rodolfo Cordeiro; Reis, Alexandre Barbosa; Lemos, Denise da Silveira; Martins Filho, Olindo Assis; Oliveira, Rodrigo Corrêa de

Human visceral leishmaniasis, one of the most important zoonoses, is caused by the protozoaLeishmania chagasi(syn. L. infantum ) and is present as a fatal disease common in South America and Europe where dogs and wild canids are the main reservoirs. A vaccine against visceral leishmaniasis would be an important tool in the control of this disease in dogs. Although the current strategies for vac-cination against...

Date: 2012   |   Origin: Oasisbr
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