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Preparação de ésteres nitrocinâmicos e avaliação da sua atividade antimicrobiana
Nascimento, Lázaro Gomes doThe present work aimed to prepare a series of esters derived from trans-2-nitrocinnamic acid, through Fischer esterification, nucleophilic substitution with halides and Mitsunobu reaction. All the derivatives were submitted to antimicrobial tests by the microdilution method in broth, and the antimicrobials chloramphenicol and nystatin as positive controls. This study resulted in the obtaining of 14 esters of tr...
Evaluation of the cytotoxicity of structurally correlated p-menthane derivatives
Andrade, Luciana Nalone; Lima, Tamires Cardoso; Amaral, Ricardo Guimarães; Pessoa, Cláudia do Ó; Moraes Filho, Manoel Odorico de; Soares, Bruno MarquesCompounds isolated from essential oils play an important role in the prevention and treatment of cancer. Monoterpenes are natural products, and the principal constituents of many essential oils. The aim of this study was to investigate the cytotoxic potential of p-menthane derivatives. Additionally, analogues of perillyl alcohol, a monoterpene with known anticancer activity, were evaluated to identify the molec...
Estudo ficoquímico e avaliação da atividade microbiológica de algas marinhas do...
Nascimento, Lázaro Gomes doSubmitted by Fernando Vieira (nandogusto6@gmail.com) on 2015-02-26T12:21:45Z No. of bitstreams: 1 LGN24022015.pdf: 851387 bytes, checksum: f30983fe268d980f12dc6ed5c14463c5 (MD5); Made available in DSpace on 2015-02-26T12:21:45Z (GMT). No. of bitstreams: 1 LGN24022015.pdf: 851387 bytes, checksum: f30983fe268d980f12dc6ed5c14463c5 (MD5); Sargassum é um gênero de algas marinhas pardas da família Sargassaceae que é ...