4 documents found, page 1 of 1
Increased risk of hepatitis E virus infection in workers occupationally exposed...
Mesquita, João; Santos-Ferreira, Nanci; Ferreira, Ana S.; Albuquerque, Carlos; Nóbrega, Carmen; Esteves, Fernando; Cruz, Rita; Vala, HelenaHepatitis E virus (HEV) is an enteric RNA virus from the family Hepeviridae with five genotypes (genotypes 1–4 and 7) known to infect humans. HEV infection is known to have a zoonotic swine origin in industrialized countries. The role of pigs and wild boars as major reservoirs for human infection is today well-established; however, the list of new animal reservoirs is ever-expanding as new HEV strains are conti...
Hepatitis E virus genotype 3 in mussels (Mytilus galloprovinciallis), Spain
Mesquita, João R.; Oliveira, Danielle; Rivadulla, Enrique; Silva, Joana Abreu; Varela, Miguel F.; Romalde, Jesús L.; Nascimento, Maria S. J.Coastal waters can become contaminated with both human waste from sewage treatment plants and runoff following manure application. Thus, shellfish produced close to land can bioaccumulate enteric viruses of human and animal origin, including zoonotic hepatitis E virus that infect both human and swine. The goal of this study was to evaluate the presence of HEV in shellfish from Galicia (NW Spain), a densely popu...
The Epidemiology of Blood-Contaminated Needlestick Injuries Among Veterinarians...
Mesquita, João R.; Sousa, Sofia I. V.; Vala, Helena; Nascimento, Maria S. J.Needlestick injuries (NIs) are considered a substantial occupational health and safety hazard in contemporary health care practice. Unlike human medicine where much effort has been devoted to reduce the incidence of these events, the same aggressive approach has not been used in veterinary medicine. This study investigated the occurrence of blood-contaminated NIs in Portuguese veterinarians. Participants of a v...
Sulfated small molecules targeting EBV in Burkitt lymphoma: from in silico scre...
Lima, Raquel T.; Seca, Hugo; Palmeira, Andreia; Fernandes, Miguel X.; Castro, Felipe; Correia-da-Silva, Marta; Nascimento, Maria S. J.; Sousa, EmíliaEpstein–Barr virus (EBV) infects more than 90% of the world population. Following primary infection, Epstein– Barr virus persists in an asymptomatic latent state. Occasionally, it may switch to lytic infection. Latent EBV infection has been associated with several diseases, such as Burkitt lymphoma (BL). To date, there are no available drugs to target latent EBV, and the existing broad-spec trum antiviral drugs...