4 documents found, page 1 of 1
Cryptococcosis by Cryptococcus neoformans/Cryptococcus gattii Species Complexes...
Nascimento,Erika; Barião,Patrícia Helena Grizante; Kress,Marcia Regina von Zeska; Vilar,Fernando Crivelenti; Santana,Rodrigo de CarvalhoAbstract INTRODUCTION: The clinical manifestations of cryptococcosis are usually associated with the infecting agents Cryptococcus neoformans (CN) and C. gattii (CG) species complexes and the host. In this study, non-HIV-infected patients, at a university hospital in southeastern Brazil, had epidemiological and clinical data associated with cryptococcal disease and isolated Cryptococcus species: CN - 24 patient...
Characterization of a Paracoccidioides spp. strain from southeastern Brazil gen...
Cocio,Tiago Alexandre; Nascimento,Erika; Kress,Marcia R. V. Z.; Bagagli,Eduardo; Martinez,RobertoAbstract Phylogenetic species of Paracoccidioides brasiliensis complex (S1a and S1b, PS2, PS3, and PS4) and Paracoccidioides lutzii are agents of paracoccidioidomycosis, an endemic fungal disease in Latin America. P. restrepiensis (PS3 genotype) was classified as monophyletic and geographically restricted to Colombia and neighboring territories. BAT (or Pb-327B) was isolated from a patient living in the southea...
Minimum concentration of Amphotericin B in serum according to the formulation, ...
Schiave,Leticia Aparecida; Nascimento,Erika; Gaspar,Gilberto Gambero; Vilar,Fernando Crivelenti; Martinez,Edson Zangiacomi; Gaitani,Cristiane Masetto deAbstract INTRODUCTION: The therapeutic efficacy of daily amphotericin B infusion is related to its maximum concentration in blood; however, trough levels may be useful in intermittent regimens of this antifungal drug. METHODS : High performance liquid chromatography (HPLC) was used to determine the minimum concentration (Cmin) of amphotericin B in the serum of patients receiving deoxycholate (D-Amph) or liposom...
Fluconazole levels in serum and cerebrospinal fluid according to daily dosage i...
Schiave,Letícia Aparecida; Nascimento,Erika; Vilar,Fernando Crivelenti; de Haes,Tissiana Marques; Takayanagui,Osvaldo MassaitiABSTRACT Fluconazole is extensively used for the treatment of candidiasis and cryptococcosis. Among other factors, successful treatment is related to appropriate fluconazole levels in blood and cerebrospinal fluid. In the present study, fluconazole levels were determined in 15 patients, 14 of whom had AIDS and 13 had neurocryptococcosis. The only selection criterion was treatment with fluconazole, which was per...