34 documents found, page 1 of 4
Pain in Charcot-Marie-Tooth disease: an update
Azevedo,Helen; Pupe,Camila; Pereira,Rouse; Nascimento,Osvaldo J. M.ABSTRACT Charcot-Marie-Tooth (CMT) disease, the most common inherited peripheral neuropathy, has pain as one of its clinical features, yet it remains underdiagnosed and undertreated. This literature review assessed data related to pain from CMT to determine its prevalence, type and importance as a symptom, which, unlike other symptoms, is likely to be treated. The research encompassed 2007 to 2017 and included ...
Brazilian Consensus for the Treatment of Multiple Sclerosis: Brazilian Academy ...
Marques,Vanessa Daccach; Passos,Giordani Rodrigues dos; Mendes,Maria Fernanda; Callegaro,Dagoberto; Lana-Peixoto,Marco AurélioABSTRACT The expanding therapeutic arsenal in multiple sclerosis (MS) has allowed for more effective and personalized treatment, but the choice and management of disease-modifying therapies (DMTs) is becoming increasingly complex. In this context, experts from the Brazilian Committee on Treatment and Research in Multiple Sclerosis and the Neuroimmunology Scientific Department of the Brazilian Academy of Neurolo...
Brazilian consensus for diagnosis, management and treatment of transthyretin fa...
Pinto,Marcus Vinicius; Barreira,Amilton Antunes; Bulle,Acary Souza; Freitas,Marcos Raimundo Gomes de; França Jr,Marcondes CavalcanteABSTRACT Transthyretin familial amyloid polyneuropathy is an autosomal dominant inherited sensorimotor and autonomic polyneuropathy, which if untreated, leads to death in approximately 10 years. In Brazil, liver transplant and tafamidis are the only disease-modifying treatments available. This review consists of a consensus for the diagnosis, management and treatment for transthyretin familial amyloid polyneuro...
Corneal confocal microscopy in a healthy Brazilian sample
Dieckmann,Gabriela; Pupe,Camila; Nascimento,Osvaldo J. M.ABSTRACT Objective This study aims to evaluate the characteristics of the corneal sub-basal plexus by performing in vivo confocal microscopy of healthy Brazilians to provide reference values for the Brazilian population. Method This study is an observational, cross-sectional, descriptive study comparing corneas from 55 healthy Brazilian individuals across the age span of 20-70 years. Results The average number ...
Currents issues in cardiorespiratory care of patients with post-polio syndrome
Orsini,Marco; Lopes,Agnaldo J.; Guimarães,Fernando S.; Freitas,Marcos R. G.; Nascimento,Osvaldo J. M.; Anna Junior,Mauricio de Sant’ABSTRACT Post-polio syndrome (PPS) is a condition that affects polio survivors years after recovery from an initial acute attack of the poliomyelitis virus. Most often, polio survivors experience a gradual new weakening in muscles that were previously affected by the polio infection. The actual incidence of cardiovascular diseases (CVDs) in individuals suffering from PPS is not known. However, there is a reason...
Simple prediction model for unfavorable outcome in ischemic stroke after intrav...
Amitrano,Daniel; Silva,Ivan Rocha Ferreira da; Liberato,Bernardo B.; Batistella,Valéria; Oliveira,Janaina; Nascimento,Osvaldo J. M.ABSTRACT Objective We aimed to develop a model to predict unfavorable outcome in patients with acute ischemic stroke treated with intravenous thrombolytic therapy (IVT), based on simple variables present on admission. Methods Retrospective analysis of acute ischemic stroke patients treated with IVT in a hospital in Rio de Janeiro. Clinical and radiographic variables were selected for analysis. Multivariate logi...
Etiological prevalence of epilepsy and epileptic seizures in hospitalized elder...
Assis,Telma Rocha de; Bacellar,Aroldo; Costa,Gersonita; Nascimento,Osvaldo J. M.Epilepsy in the elderly has high incidence and prevalence and is often underecognized. Objective To describe etiological prevalence of epilepsy and epileptic seizures in elderly inpatients. Methods Retrospective analysis was performed on elderly patients who had epilepsy or epileptic seizures during hospitalization, from January 2009 to December 2010. One hundred and twenty patients were enrolled. They were div...
Mortality predictors of epilepsy and epileptic seizures among hospitalized elderly
Assis,Telma M. R; Bacellar,Aroldo; Costa,Gersonita; Nascimento,Osvaldo J. M.Epilepsy and epileptic seizures are common brain disorders in the elderly and are associated with increased mortality that may be ascribed to the underlying disease or epilepsy-related causes.Objective To describe mortality predictors of epilepsy and epileptic seizures in elderly inpatients.Method Retrospective analysis was performed on hospitalized elderly who had epilepsy or epileptic seizures, from January 2...
Prevalence of temporomandibular disorders symptoms in patients with multiple sc...
Carvalho,Lucas S. C.; Matta,André P. C.; Nascimento,Osvaldo J. M.; Guimarães,Antônio S.; Rodrigues,Luciane R.The aim of the present study was to assess the prevalence of symptoms of temporomandibular disorders (TMD) in patients with the relapsing-remitting form of multiple sclerosis (MS), the relationship between TMD and the severity of MS, and the presence of TMD symptoms in the evaluated groups. Sixty individuals were evaluated: 30 patients diagnosed with relapsing-remitting MS and 30 control individuals matched for...
Cardiac 123I-MIBG uptake in de novo Brazilian patients with Parkinson's disease...
Leite,Marco Antonio Araujo; Nascimento,Osvaldo J. M.; Pereira,João Santos; Amaral,Clayton; Mesquita,Cláudio T.; Azevedo,Jader C.; Brito,Adriana S. X. deMyocardial scintigraphy with meta-iodo-benzyl-guanidine (123I cMIBG) has been studied in Parkinson's disease (PD), especially in Asian countries, but not in Latin America. Most of these studies include individuals with PD associated to a defined dysautonomia. Our goal is to report the cardiac sympathetic neurotransmission in de novo Brazilian patients with sporadic PD, without clinically defined dysautonomia. W...