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New Alkaloids from Margaritopsis carrascoana (Rubiaceae)
Nascimento,Raimundo R. G.; Pimenta,Antônia T. A.; Lima Neto,Pedro de; C. Junior,José R.; Costa-Lotufo,Letícia V.; Ferreira,Elthon G.Two new alkaloids containing Nb-methyl-triptamine units linked to bis-quinoline moieties, N-8”-formyl-calycosidine and N-8”-methyl-N-1’-demethyl-iso-calycosidine, were isolated from the aerial part of Margaritopsis carrascoana, along with known calycosidine and hodgkinsine. The cytotoxicity of the isolated alkaloids has been evaluated against cancer cell lines. The first two compounds showed only weak activity ...
Date: 2015
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Origin: Oasisbr