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Temperature frequency and mortality: Assessing adaptation to local temperature

Wu, Y; Wen, B; Gasparrini, A; Armstrong, B; Sera, F; Lavigne, E; Li, S; Guo, Y; Overcenco, A; Urban, A; Schneider, A; Entezari, A; Vicedo-Cabrera, AM

Assessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on mortality and temperature from 757 locations in 47 countries/regions during 1979–2020. We used a two-stage time series design to assess the association between temperature frequency and all-cause mortality. The results were pooled ...


Global and Regional Cardiovascular Mortality Attributable to Nonoptimal Tempera...

Hundessa, S; Huang, W; Zhao, Q; Wu, Y; Wen, B; Alahmad, B; Armstrong, B; Gasparrini, A; Sera, F; Tong, S; Madureira, J; Kyselý, J; Schwartz, J

Background: The association between nonoptimal temperatures and cardiovascular mortality risk is recognized. However, a comprehensive global assessment of this burden is lacking. Objectives: The goal of this study was to assess global cardiovascular mortality burden attributable to nonoptimal temperatures and investigate spatiotemporal trends. Methods: Using daily cardiovascular deaths and temperature data from...


Temperature-mortality associations by age and cause: a multi-country multi-city...

Scovronick, N; Sera, F; Vu, B; Vicedo-Cabrera, AM; Roye, D; Tobias, A; Seposo, X; Forsberg, B; Guo, Y; Li, S; Honda, Y; Abrutzky, R

"Background: Heterogeneity in temperature-mortality relationships across locations may partly result from differences in the demographic structure of populations and their cause-specific vulnerabilities. Here we conduct the largest epidemiological study to date on the association between ambient temperature and mortality by age and cause using data from 532 cities in 33 countries. Methods: We collected daily te...


Fluctuating temperature modifies heat-mortality association around the globe

Wu, Y; Wen, B; Li, S; Gasparrini, A; Tong, S; Overcenco, A; Urban, A; Schneider, A; Entezari, A; Vicedo-Cabrera, AM; Zanobetti, A; Analitis, A; Zeka, A

Studies have investigated the effects of heat and temperature variability (TV) on mortality. However, few assessed whether TV modifies the heat-mortality association. Data on daily temperature and mortality in the warm season were collected from 717 locations across 36 countries. TV was calculated as the standard deviation of the average of the same and previous days’ minimum and maximum temperatures. We used l...


Global, regional, and national burden of mortality associated with short-term t...

Wu, Y; Li, S; Zhao, Q; Wen, B; Gasparrini, A; Tong, S; Overcenco, A; Urban, A; Schneider, A; Entezari, A; Vicedo-Cabrera, AM; Zanobetti, A; Analitis, A

Background: Increased mortality risk is associated with short-term temperature variability. However, to our knowledge, there has been no comprehensive assessment of the temperature variability-related mortality burden worldwide. In this study, using data from the MCC Collaborative Research Network, we first explored the association between temperature variability and mortality across 43 countries or regions. Th...


Mortality risk attributable to wildfire-related PM(2·5) pollution: a global tim...

Chen, G; Guo, Y; Yue, X; Tong, S; Gasparrini, A; Bell, ML; Armstrong, B; Schwartz, J; Jaakkola, JJK; Zanobetti, A; Lavigne, E; Nascimento Saldiva, PH

Background Many regions of the world are now facing more frequent and unprecedentedly large wildfires. However, the association between wildfire-related PM2·5 and mortality has not been well characterised. We aimed to comprehensively assess the association between short-term exposure to wildfire-related PM2·5 and mortality across various regions of the world. Methods For this time series study, data on daily co...


Global, regional, and national burden of mortality associated with non-optimal ...

Zhao, Q; Guo, Y; Ye, T; Gasparrini, A; Tong, S; Overcenco, A; Urban, A; Schneider, A; Entezari, A; Vicedo-Cabrera, AM; Zanobetti, A; Analitis, A

Background: Exposure to cold or hot temperatures is associated with premature deaths. We aimed to evaluate the global, regional, and national mortality burden associated with non-optimal ambient temperatures. Methods: In this modelling study, we collected time-series data on mortality and ambient temperatures from 750 locations in 43 countries and five meta-predictors at a grid size of 0·5° × 0·5° across the gl...


Projections of excess mortality related to diurnal temperature range under clim...

Lee, W; Kim, Y; Sera, F; Gasparrini, A; Park, R; Michelle Choi, H; Prifti, K; Bell, ML; Abrutzky, R; Guo, Y; Tong, S

Background. Various retrospective studies have reported on the increase of mortality risk due to higher diurnal temperature range (DTR). This study projects the effect of DTR on future mortality across 445 communities in 20 countries and regions. Methods. DTR-related mortality risk was estimated on the basis of the historical daily time-series of mortality and weather factors from Jan 1, 1985, to Dec 31, 2015, ...


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