5 documents found, page 1 of 1
MHC Variants Associated With Symptomatic Versus Asymptomatic SARS-CoV-2 Infecti...
Castelli, Erick C. [UNESP]; de Castro, Mateus V.; Naslavsky, Michel S.; Scliar, Marilia O.; Silva, Nayane S. B. [UNESP]; Andrade, Heloisa S. [UNESP]Made available in DSpace on 2022-04-29T08:46:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-28; Center for Information Technology; Center for Scientific Review; National Institutes of Health; Office of Extramural Research, National Institutes of Health; Office of Research Infrastructure Programs, National Institutes of Health; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fu...
HLA-G genetic diversity and evolutive aspects in worldwide populations
Castelli, Erick C. [UNESP]; de Almeida, Bibiana S.; Muniz, Yara C. N.; Silva, Nayane S. B. [UNESP]; Passos, Marília R. S. [UNESP]Made available in DSpace on 2022-04-29T08:46:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents substantial nucleotide variability in its regulatory regions. However, it encodes a limited number of proteins compared to classical HLA class I genes. We characterized the HLA-G genetic variability in 4640 individuals from 88 di...
Recurrence of COVID-19 associated with reduced T-cell responses in a monozygoti...
De Castro, Mateus V.; Santos, Keity S.; Apostolico, Juliana S.; Fernandes, Edgar R.; Almeida, Rafael R.; Levin, Gabriel; Magawa, Jhosiene Y.Made available in DSpace on 2022-04-29T08:46:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Recurrence of COVID-19 in recovered patients has been increasingly reported. However, the immune mechanisms behind the recurrence have not been thoroughly investigated. The presence of neutralizing antibodies (nAbs) in recurrence/reinfection cases suggests that other types of immune response are involve...
Whole-genome sequencing of 1,171 elderly admixed individuals from São Paulo, Br...
Naslavsky, Michel S.; Scliar, Marilia O.; Yamamoto, Guilherme L.; Wang, Jaqueline Yu Ting; Zverinova, Stepanka; Karp, Tatiana; Nunes, KellyMade available in DSpace on 2022-04-29T08:46:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-12-01; National Institute of General Medical Sciences; As whole-genome sequencing (WGS) becomes the gold standard tool for studying population genomics and medical applications, data on diverse non-European and admixed individuals are still scarce. Here, we present a high-coverage WGS dataset of 1,171 highly a...
Detection of small copy number variations (CNVs) in autism spectrum disorder (A...
Moreira, Eloisa S.; Silva, Isabela M. W.; Lourenco, Naila; Moreira, Danielle P.; Ribeiro, Cintia M.; Martins, Ana Luiza B. [UNESP]Made available in DSpace on 2018-11-26T17:55:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-03-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Autism spectrum disorder (ASD) has a strong genetic basis and advances in genomic scanning methods have resulted in the identification of the underlying alterations in abo...