10 documents found, page 1 of 1

The use of hemodialysis in hypercalcemic crisis secondary to primary hyperparat...

ABSTRACT Severe hypercalcemia can be either acute or decompensate from a chronic state to a medical emergency, the hypercalcemic crisis. The presence of symptoms such as altered mental status or potentially fatal ECG abnormalities demand an expeditious decrease in serum calcium levels. Standard medical therapy consists of vigorous volume replacement, calcitonin and, depending on the etiology, bisphosphonates, c...

Treatment of lupus nephritis - past, present and (near) future

The management of lupus nephritis is challenging for most nephrologists. Many trials have brought only a certain degree of evidence to the diagnosis and treatment of this disease, and many questions remain unanswered. In this review, we will explore the path traveled so far and the steps that are likely to happen in the near future.

Effectiveness of sucroferric oxyhydroxide in patients on on-line hemodiafiltrat...

Abstract Introduction: Hyperphosphatemia is a serious consequence of chronic kidney disease and has been associated with an increased risk for cardiovascular disease. Controlling serum phosphorus levels in patients on dialysis is a challenge for the clinicians and implies, in most cases, the use of phosphate binders (PB). Part of the reason for this challenge is poor adherence to treatment because of the high p...

Pathology turned its back on semiology

Are high flow arteriovenous accesses associated with worse haemodialysis?

ABSTRACT Introduction: An arteriovenous (AV) access flow (Qa) of 400 mL/min is usually sufficient for an effective hemodialysis (HD), but some accesses continue developing and become high flow accesses (HFA). Some authors postulated that an HFA might shift a significant portion of dialyzed blood from the cardiac output, which could decrease HD efficiency and lead to volume overload. Objective: The aim of our st...

Prostate involvement in granulomatosis with polyangiitis: response to rituximab...

Granulomatosis with polyangiitis is an autoimmune vasculitic condition strongly associated with anti-neutrophil cytoplasm antibodies. It classically affects the respiratory tract and the kidney, but it can manifest in a multitude of other organs. Urological involvement is uncommon and can be difficult to diagnose. We present two cases of GPA with prostatic involvement, with distinct clinical manifestations. Bot...

Bartter syndrome - report of an unusual late presentation case and brief review

Bartter syndrome is a rare autosomal recessive condition caused by the inability of the thick ascending limb to reabsorb filtered sodium and chloride. Types I and II, called antenatal Bartter syndrome, are the most severe, and manifest in-utero as polyhydramnios, preterm labour, salt wasting, life-threatening volume depletion, and severe hypokalemic metabolic alkalosis, with a high early mortality rate if untre...

Henoch-Schönlein purpura associated with pulmonary adenocarcinoma

Introduction: The Henoch-Schönlein purpura (HSP) is an immunoglobulin A (IgA)-mediated smallvessel systemic vasculitis, rare in adults. The association with solid tumours has been described, especially with lung cancer. Case Report: We present the case of a 60-year-old Caucasian male, diag- nosed with lung adenocarcinoma that underwent surgical resection without (neo)adjuvant theraphy. Two months latter he was ...

Early renal protocol biopsies: for some but not for all renal transplant patients?

Subclinical rejection following renal transplant is associated with worse outcomes, which can be prevented if recognized early. Protocol allograft biopsies have emerged as an option to identify and allow treatment of subclinical rejection, but optimal timing for their performance is not established. We retrospectively evaluated a cohort of 52 low immunological risk patients, who were submitted, from 2007 to 201...

Long nocturnal dialysis: A single-centre experience

The institution of intensified dialysis regimens (as long treatment time, with reduced ultrafiltration per hour) has been associated with decreased morbidity and mortality in patients with end-stage chronic kidney disease. The performance of the haemodialysis session during the night interval emerged as logical, since it is an “idle” period, and has been associated with better small molecule dialysis, better bl...