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A multi-biomarker approach for the early assessment of the toxicity of hospital...
Afsa, Sabrine; Vieira, Madalena; Nogueira, Ana Filipa; Mansour, Hedi Ben; Nunes, BrunoHospital wastewater (HWW) contains different hazardous substances resulting from a combination of medical and non-medical activities of hospitals, including pharmaceutical residues. These substances may represent a threat to the aquatic environment if they do not follow specific treatment processes. Therefore, we aimed to investigate the effects of the untreated effluent collected from a general hospital in Mah...
Cholinesterases of marine fish: characterization and sensitivity towards specif...
Vieira, Madalena; Nunes, BrunoInhibition of cholinesterases has been frequently used as a biomarker for contamination of aquatic environments, because these enzymes are frequent targets for toxic effects of contaminants, such as insecticides derived from phosphoric and carbamic acids. However, this enzyme is also responsive to other contaminants, including metals. The use of cholinesterase inhibition as effect criterion in ecotoxicology stu...
Biomarker-based assessment of the toxicity of the antifungal clotrimazol to the...
Vieira, Madalena; Soares, Amadeu M. V. M.; Nunes, B.Among the vast list of xenobiotics that may promote harmful effects in aquatic ecosystems, pharmaceuticals are currently a prominent class due to their ability to persist in these environments and also due to the lack of information regarding their effects on the different components of the aquatic biota. Antifungals in particular, despite their massive use, are not extensively studied in environbmental terms. ...
Simultaneous determination of Deoxynivalenol, Deoxynivalenol-3-Glucoside and Ni...
Trombete, F.; Barros, A.; Vieira, Madalena; Saldanha, Tatiana; Venâncio, Armando; Fraga, M.Deoxynivalenol-3-glucoside (D3G) is a modified mycotoxin formed by the metabolism of plants through the conjugation of deoxynivalenol (DON) with glucose. Toxicology studies of D3G for human and animal health are still under investigation, and the development of practical and reliable methods for its direct determination, especially in cereal matrices, is of great importance. In the present study, a methodology ...