4 documents found, page 1 of 1
Case report
Vilhais, Guilherme; Alpuim Costa, Diogo; Fontes-Sousa, Mário; Ribeiro, Pedro Casal; Martinho, Filipa; Botelho de Sousa, CarolinaPublisher Copyright: Copyright © 2024 Vilhais, Alpuim Costa, Fontes-Sousa, Ribeiro, Martinho, Botelho de Sousa, Santos, Negreiros, Canastra, Borralho, Guia Pereira, Marçal, Germano Sousa, Chaleira, Rocha, Calhau and Faria.; Locally advanced breast cancer poses significant challenges to the multidisciplinary team, in particular with hormone receptor (HR) positive, HER2-negative tumors that classically yield lowe...
Breast Cancer Survivors and Healthy Women
Caleça, Telma; Ribeiro, Pedro; Vitorino, Marina; Menezes, Maria; Sampaio-Alves, Mafalda; Mendes, Ana Duarte; Vicente, Rodrigo; Negreiros, IdaIn this first analysis, samples from 23 BC survivors (group 1) and 291 healthy female controls (group 2) were characterised through the V3 and V4 regions that encode the “16S rRNA” gene of each bacteria. The samples were sequenced by next-generation sequencing (NGS), and the taxonomy was identified by resorting to Kraken2 and improved with Bracken, using a curated database called ‘GutHealth_DB’. The α and β-div...
Human Microbiota and Breast Cancer—Is There Any Relevant Link?—A Literature Rev...
Alpuim Costa, Diogo; Nobre, José Guilherme; Batista, Marta Vaz; Ribeiro, Catarina; Calle, Catarina; Cortes, Alfonso; Marhold, Maximilian; Negreiros, IdaBreast cancer (BC) is the most common malignancy and the second cause of cancer-specific death in women from high-income countries. Recently, gut microbiota dysbiosis emerged as a key player that may directly and/or indirectly influence development, treatment, and prognosis of BC through diverse biological processes: host cell proliferation and death, immune system function, chronic inflammation, oncogenic sign...
Expression of hla-dr in cytotoxic t lymphocytes
Saraiva, Diana P.; Azeredo-Lopes, Sofia; Antunes, Ana; Salvador, Rute; Borralho, Paula; Assis, Beatriz; Pereira, Isabel L.; Seabra, Zita; Negreiros, IdaFunding Information: Funding: This work was supported by Terry Fox Research Grant 2019 from Liga Portuguesa Contra o Cancro; Clinical Research Prize 2018 from Consortium Tagus Tank; Fundação para a Ciência e Tecnologia (PD/BD/114023/2015 for DPS and SFRH/BD/148422/2019 for RS) and iNOVA4Health (UIDB/04462/2020, DAI/2019/46). Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.; Neoadju...