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CSF Tau proteins reduce misdiagnosis of sporadic Creutzfeldt-Jakob disease susp...

Leitão, MJ; Baldeiras, I; Almeida, MR; Ribeiro, MH; Santos, AC; Ribeiro, M; Tomás, J; Rocha, S; Santana, I; Oliveira, CR

Cerebrospinal fluid (CSF) 14-3-3 protein supports sporadic Creutzfeldt-Jakob (sCJD) diagnosis, but often leads to weak-positive results and lacks standardization. In this study, we explored the added diagnostic value of Total Tau (t-Tau) and phosphorylated Tau (p-Tau) in sCJD diagnosis, particularly in the cases with inconclusive 14-3-3 result. 95 definite sCJD and 287 patients without prion disease (non-CJD) w...

Date: 2016   |   Origin: Repositório Científico do Hospital de Braga
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