2 documents found, page 1 of 1
Development, cytotoxicity and eye irritation profile of a new sunscreen formula...
Barbosa, Thallysson Carvalho; Nascimento, Lívia Éven Dias; Bani, Cristiane; Almeida, Taline; Nery, Marcelo; Santos, Rafael SilvaThe objective of this work was to characterize the toxicological profile of a newly developed sunscreen formulation based on polymeric nanocapsules (NCs) loading benzophenone-3 (BZP3). NCs composed of poly(ε-caprolactone) carrot oil and Pluronic® F68 were produced by emulsification-diffusion method. Their mean particle size (Z-Ave) ranged from 280 to 420 nm, polydispersity index (PDI) was below 0.37, while zeta...
Praziquantel-solid lipid nanoparticles produced by supercritical carbon dioxide...
Andrade, Luciana N.; Oliveira, Daniele M. L.; Chaud, Marco V.; Alves, Thais F. R.; Nery, Marcelo; da Silva, Classius F.; Gonsalves, Joyce K. C.Solid lipid nanoparticles (SLNs) can be produced by various methods, but most of them are difficult to scale up. Supercritical fluid (SCF) is an important tool to produce micro/nanoparticles with a narrow size distribution and high encapsulation efficiency. The aim of this work was to produce cetyl palmitate SLNs using SCF to be loaded with praziquantel (PZQ) as an insoluble model drug. The mean particle size (...