Encontrados 5 documentos, a visualizar página 1 de 1
Metformin reverses infertility in a mouse model of endometriosis: unveiling dis...
Neto, AC; Botelho, M; Rodrigues, AR; Lamas, S; Araújo, B; Guimarães, JT; Gouveia, AM; Almeida, H; Neves, D" Research question: Does metformin reverse endometriosis-associated infertility? Design: Endometriosis was induced by transplanting uterus fragments from B6CBAF1 mice into recipients of the same strain. The mice were divided into groups: endometriosis (End, n = 24), sham-operated (Sham, n = 12), endometriosis with metformin (0.5mg/ml) orally administered for 3 months (EndMet, n = 21) and sham-operated metformi...
The Unmet Needs for Studying Chronic Pelvic/Visceral Pain Using Animal Models
Neto, AC; Santos Pereira, M; Abreu Mendes, P; Neves, D; Almeida, H; Cruz, F; Charrua A.<jats:p>The different definitions of chronic pelvic/visceral pain used by international societies have changed over the years. These differences have a great impact on the way researchers study chronic pelvic/visceral pain. Recently, the role of systemic changes, including the role of the central nervous system, in the perpetuation and chronification of pelvic/visceral pain has gained weight. Consequently, rese...
Metformin Prevents Endothelial Dysfunction in Endometriosis through Downregulat...
Martins, AF; Neto, AC; Rodrigues, AR; Oliveira, SM; Sousa Mendes, C; Leite-Moreira, AF; Gouveia, Alexandra; Almeida, Henrique; Neves, D
Follicular Fluid redox involvement for ovarian follicle growth
Freitas, C; Neto, AC; Matos, L; Silva, E; Ribeiro, Â; Silva-Carvalho, JL; Almeida, HenriqueAs the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cells and the follicular fluid (FF).In contrast to the dynamic nature of cells, the fluid compartment appears as a reservoir rich in biomolecules. In some aspects, it is similar to the plasma, but it also exhi...
Follicular Fluid redox involvement for ovarian follicle growth
Freitas, C; Neto, AC; Silva, E; Ribeiro, Â; Silva Carvalho, JL; Almeida, H; Matos, LilianaAs the human ovarian follicle enlarges in the course of a regular cycle or following controlled ovarian stimulation, the changes in its structure reveal the oocyte environment composed of cumulus oophorus cells and the follicular fluid (FF). In contrast to the dynamic nature of cells, the fluid compartment appears as a reservoir rich in biomolecules. In some aspects, it is similar to the plasma, but it also exh...