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Rotavirus alphagastroenteritidis: circulating strains after the introduction of...

Vita, Dikudila G.; Santiso-Bellón, Cristina; Lemos, Manuel; Neto, Zoraima; Fortes-Gabriel, Elsa; Brito, Miguel; Sebastião, Cruz S.

Rotavirus alphagastroenteritidis (R. alphagastroenteritidis) remains the leading cause of pediatric diarrhea. Although Angola introduced Rotarix®, the human monovalent R. alphagastroenteritidis vaccine since 2014 as part of its routine childhood immunization program, no follow-up study has been conducted. This study aimed to evaluate the distribution of R. alphagastroenteritidis genotypes among children under f...


Dengue virus among HIV-infected pregnant women attending antenatal care in Luan...

Sebastião, Cruz S.; Neto, Zoraima; Jandondo, Domingos; Mirandela, Marinela; Morais, Joana; Brito, Miguel

The dissemination of the dengue virus (DENV) in endemic regions with HIV is a public health concern with greater importance when there is evidence of vertical transmission of DENV during pregnancy. Herein, we investigated DENV among HIV-infected pregnant women in Luanda, the capital city of Angola. This was part of a cross-sectional study carried out on 42 pregnant women newly diagnosed with HIV. A total of 36 ...


HIV, hepatitis B virus, hepatitis C virus, and syphilis among pregnant women at...

Sebastião, Cruz S.; Neto, Zoraima; Jandondo, Domingos; Mirandela, Marinela; Morais, Joana; Brito, Miguel

Infectious diseases during pregnancy remain a public health concern, especially in a resource-limited setting. The study aimed to determine the seroprevalence and determinants of HIV and co-infection with hepatitis B virus (HBV), hepatitis C virus (HCV), and syphilis among pregnant women attending antenatal care in Luanda, the capital city of Angola. A cross-sectional study was conducted with 1612 pregnant wome...


Metagenomic sequencing with spiked primer enrichment for viral diagnostics and ...

Deng, Xianding; Achari, Asmeeta; Federman, Scot; Yu, Guixia; Somasekar, Sneha; Bártolo, Inês; Yagi, Shigeo; Mbala-Kingebeni, Placide; Kapetshi, Jimmy

Metagenomic next-generation sequencing (mNGS), the shotgun sequencing of RNA and DNA from clinical samples, has proved useful for broad-spectrum pathogen detection and the genomic surveillance of viral outbreaks. An additional target enrichment step is generally needed for high-sensitivity pathogen identification in low-titre infections, yet available methods using PCR or capture probes can be limited by high c...


Author Correction: Metagenomic sequencing with spiked primer enrichment for vir...

Deng, Xianding; Achari, Asmeeta; Federman, Scot; Yu, Guixia; Somasekar, Sneha; Bártolo, Inês; Yagi, Shigeo; Mbala-Kingebeni, Placide; Kapetshi, Jimmy


Genetic diversity and drug resistance of HIV-1 among infected pregnant women ne...

Sebastião, Cruz S.; Neto, Zoraima; Jesus, Carlos S. de; Mirandela, Marinela; Jandondo, Domingos; Couto-Fernandez, José C.; Tanuri, Amilcar

Monitoring genetic diversity and drug resistance mutations (DRMs) is critical for understanding HIV epidemiology. Here, we report HIV-1 genetic diversity and DRMs in blood samples from 42 HIV-positive pregnant women naive to antiretroviral therapy (ART), in Luanda. The samples were subjected to nested-PCR, followed by sequencing of the HIV-1 pol gene, targeting the protease and reverse transcriptase fragments. ...


NDVI and LST extraction of MODIS data under a GIS open source application - Ric...

Teodoro, Ana Cláudia; Duarte, Lia; Barradas, Patrícia; Mateus, Teresa Letra; Neto, Zoraima

Fevers of unknown origin can have different aetiologies. The overlapping symptomatology of rickettsial infection and other endemic diseases that cause fever leads to a misdiagnosis or under-diagnosis of spotted fever group of Rickettsia (SFGR). To better understand the epidemiology of this vector-borne disease in Angola, a comprehensive seroprevalence study was conducted investigating the exposure to SFGR in a ...

Date: 2018   |   Origin: Repositório Científico IPVC

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