4 documents found, page 1 of 1
Practical Guidance on the Detection of NTRK Fusions in Sarcomas: Current Status...
Fernandes, I; Macedo, D; Gouveia, E; Ferreira, A; Lima, J; Lopez, D; Melo-Alvim, C; Carvalho, A; Tavares, P; Rodrigues-Santos, P; Cardoso, PSarcomas are a rare and heterogeneous group of mesenchymal malignant tumors and account for approximately 1% of all adult cancers and around 20% of all pediatric solid tumors in Europe. Technology advances have enabled a more accurate and efficient characterization of the molecular mechanisms underlying the pathogenesis of sarcoma subtypes and revealed novel and unexpected therapeutic targets with prognostic/pr...
Hyperbaric Oxygen Therapy as a Complementary Treatment in Glioblastoma—A Scopin...
Alpuim Costa, D; Sampaio-Alves, M; Netto, E; Fernandez, G; Oliveira, E; Teixeira, A; Daniel, PM; Bernardo, GS; Amaro, CGlioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults. The mainstay of management for GBM is surgical resection, radiation (RT), and chemotherapy (CT). Even with optimized multimodal treatment, GBM has a high recurrence and poor survival rates ranging from 12 to 24 months in most patients. Recently, relevant advances in understanding GBM pathophysiology have opened new avenues for...
Hyperbaric Oxygen Therapy as a Complementary Treatment in Glioblastoma—A Scopin...
Alpuim Costa, D; Sampaio-Alves, M; Netto, E; Fernandez, G; Oliveira, E; Teixeira, A; Daniel, PM; Bernardo, GS; Amaro, CGlioblastoma (GBM) is the most common and aggressive malignant brain tumor in adults. The mainstay of management for GBM is surgical resection, radiation (RT), and chemotherapy (CT). Even with optimized multimodal treatment, GBM has a high recurrence and poor survival rates ranging from 12 to 24 months in most patients. Recently, relevant advances in understanding GBM pathophysiology have opened new avenues for...
New Perspectives on the Conservative Management of Osteoradionecrosis of the Ma...
Alpuim Costa, D; Porfírio Costa, T; Netto, E; Joaquim, N; Ventura, I; Pratas, AC; Winckler, P; Pires Silva, I; Pinho, AC; Goulão Sargento, IOver the last decades, several therapeutic options were considered in the treatment of the osteoradionecrosis (ORN) of the mandible, including supportive measures, ultrasound therapy, corticosteroids, hyperbaric oxygen, surgical resection with reconstruction, and, more recently, drugs capable of reversing the fibroatrophic process. Once established, the ORN does not spontaneously disappear and a standard treatm...