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Structural Aspects of the Distinct Biochemical Properties of Glutaredoxin 1 and...

Made available in DSpace on 2022-04-28T20:48:13Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-01-23; Glutaredoxins (Grxs) are small (9-12 kDa) heat-stable proteins that are ubiquitously distributed. In Saccharomyces cerevisiae, seven Grx enzymes have been identified. Two of them (yGrx1 and yGrx2) are dithiolic, possessing a conserved Cys-Pro-Tyr-Cys motif. Here, we show that yGrx2 has a specific activi...

Estudo aponta sistema de enzimas antioxidantes como alvo para o desenvolvimento...

Effects of serine or threonine in the active site of typical 2-cys prx on hyper...

Made available in DSpace on 2022-05-01T05:29:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-07-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Typical 2-Cys peroxiredoxins (2-Cys Prx) are ubiquitous Cys-based peroxidases, which are stable as decamers in the reduced state, and may dissociate into dimers upon disulfide bond formation. A peroxidatic Cys (CP) takes part of a catalytic ...

Dissecting the molecular mechanisms of mitochondrial import and maturation of p...

Substrate and product-assisted catalysis: molecular Aspects behind structural s...

Reduction of sulfenic acids by ascorbate in proteins, connecting thiol-dependen...

Made available in DSpace on 2020-12-12T02:15:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-08-20; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidad de la República Uruguay; Sulfenic acids are the primary product of thiol oxidation by hydrogen peroxide and other oxidants. Several aspects of sulfenic acid for...

Impaired antioxidant capacity causes a disruption of metabolic homeostasis in s...

Made available in DSpace on 2019-10-06T16:49:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-09-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); This study examined particularly relevant redox pathways such as glycolysis, pentose phosphate pathway (PPP), metHb reductase and nucleotide metabolism, in order to better ...

Biochemical and Structural Characterization of 1-Cys Peroxiredoxin from the Hum...

Made available in DSpace on 2019-10-04T13:28:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-11-01; Univ Sao Paulo, Sao Paulo, Brazil; Univ Fed Sao Carlos, Sao Carlos, SP, Brazil; Univ Estadual Paulista, Sao Paulo, Brazil; Univ Estadual Paulista, Sao Paulo, Brazil

Roles of Ohr (a Cys based peroxidase) and OhrR (a redox regulated transcription...

Identification and characterization of reduction agents of 1-Cys peroxiredoxins...