14 documents found, page 1 of 2

Consenso Português para o Diagnóstico e Gestão Clínica da Demência com Corpos d...

A demência com corpos de Lewy é uma causa comum de demência, provocando a perda progressiva de funções cognitivas e capacidades motoras, alterações comportamentais, e perda de autonomia, com compromisso da qualidade de vida dos doentes e seus familiares. Apesar de ser a segunda causa mais frequente de demência neurodegenerativa, o diagnóstico mantém-se um desafio, devido à sua apresentação clínica heterogénea, ...

Consenso Português para o diagnóstico e gestão clínica da demência com corpos d...

Lewy body dementia is a common cause of dementia leading to the progressive deterioration of cognitive function and motor skills, behavioral changes, and loss of autonomy, impairing the quality of life of patients and their families. Even though it is the second leading cause of neurodegenerative dementia, diagnosis is still challenging, due to its heterogenous clinical presentation, especially in the early sta...

Consenso Português para o Diagnóstico e Gestão Clínica da Demência com Corpos d...

Lewy body dementia is a common cause of dementia leading to the progressive deterioration of cognitive function and motor skills, behavioral changes, and loss of autonomy, impairing the quality of life of patients and their families. Even though it is the second leading cause of neurodegenerative dementia, diagnosis is still challenging, due to its heterogenous clinical presentation, especially in the early sta...

Portuguese Consensus on the Diagnosis and Management of Lewy Body Dementia (POR...

Lewy body dementia is a common cause of dementia leading to the progressive deterioration of cognitive function and motor skills, behavioral changes, and loss of autonomy, impairing the quality of life of patients and their families. Even though it is the second leading cause of neurodegenerative dementia, diagnosis is still challenging, due to its heterogenous clinical presentation, especially in the early sta...

A retrospective study suggests that chronic insomnia behaves as a neurodegenera...

Insomnia is a prevalent sleep disorder. We examined chronic insomnia in terms of subjective and objective measures, according to self-reported duration of disorder. 443 patients were included from a sleep clinic diagnosed with chronic insomnia (ICSD3 criteria). Patients were retrospectively evaluated in terms of medical interview, sleep questionnaires, a standard polysomnography study, and subdivided in subgrou...

Gender-related demographic, polysomnographic, cognitive and psychological facto...

Neuromelanin magnetic resonance imaging of the Substantia Nigra in LRRK2-relate...

Neuromelanin magnetic resonance imaging of the substantia nigra in LRRK2-relate...

Specific T-weighted MRI sequences are able to detect SN neuromelanin (NM) signal changes and accurately discriminate Parkinson’s disease (PD) patients from controls. The study of NM-MRI in PD patients carrying a LRRK2 gene mutation (LRRK2-PD) could contribute to further uncover LRRK2-associated phenotype. Albeit considered to largely overlap idiopathic PD (iPD), differences have been described. Furthermore, the...

End of OSLER test sessions in Parkinson’s disease do not correspond to true sle...

The aim of the present study was to evaluate the correlation between the end of an Oxford sleep resistance (OSLER) test session and a neurophysiological marker of sleep onset in Parkinson’s disease (PD) patients. Single center study was conducted in PD patients with excessive daytime sleepiness [Epworth sleepiness scale (ESS) >9]. The OSLER test was conducted with a concomitant electroencephalography (EEG), ele...

Substantia nigra neuromelanin-MR imaging differentiates essential tremor from P...

Background: Essential tremor (ET) is a very common movement disorder that has no diagnostic markers. Differentiation with Parkinson's disease (PD) can be clinically challenging in some cases, with a high rate of misdiagnosis. Magnetic resonance imaging (MRI) studies have been able to identify neuromelanin changes in the substantia nigra (SN) of PD patients, but they have thus far not been investigated in ET. In...