5 documents found, page 1 of 1
Concepts for the development of person-centred, digitally-enabled, Artificial I...
Bousquet, J; Schünemann, HJ; Sousa-Pinto, B; Zuberbier, T; Togias, A; Samolinski, B; Bedbrook, A; Czarlewski, W; Hofmann-Apitius, M; Litynska, JThe traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own life based on their lived experiences. Improving healthcare safety, quality and coordination, as well as quality of life, are important aims in the care of patients with chronic conditions. Person-centred care needs to ensure that people's v...
Determinants of the Use of Health and Fitness Mobile Apps by Patients With Asth...
Neves, AL; Jácome, C; Taveira-Gomes, T; Pereira, AM; Prates, S; Almeida, R; Amaral, RBackground: Health and fitness apps have potential benefits to improve self-management and disease control among patients with asthma. However, inconsistent use rates have been reported across studies, regions, and health systems. A better understanding of the characteristics of users and nonusers is critical to design solutions that are effectively integrated in patients' daily lives, and to ensure that these ...
Time-dependence of cardiac biomarker levels in newborns with congenital heart d...
Neves, AL; Cabral, M; Leite-Moreira, A; Monterroso, J; Ramalho, C; Guimaraes, H; Barros, H; Guimaraes, JT; Henriques-Coelho, T; Areias, JC
Myocardial Injury Biomarkers in Newborns with Congenital Heart Disease
Neves, AL; Cabral, M; Leite-Moreira, A; Monterroso, J; Ramalho, C; Guimarães, H; Barros, H; Guimarães, JT; Henriques-Coelho, T; Areias, JCBACKGROUND:Troponin I, myoglobin, and creatine kinase-MB mass (CK-MB) are biomarkers of cardiomyocyte injury widely used in the management of adult patients. The role of these biomarkers in newborns is still not established. The purpose of this study was to evaluate the value of cardiac injury biomarkers in newborns with congenital heart disease. METHODS:From August 2012 to January 2014, 34 newborns with a pren...
Thymulin inhibits monocrotaline-induced pulmonary hypertension modulating inter...
Henriques-Coelho, T; Oliveira, SM; Moura, RS; Roncon-Albuquerque R, Jr.; Neves, AL; Santos, M; Nogueira-Silva, C; La Fuente Carvalho, FThe pathogenesis of pulmonary hypertension (PH) includes an inflammatory response. Thymulin, a zinc-dependent thymic hormone, has important immunobiological effects by inhibiting various proinflammatory cytokines and chemokines. We investigated morphological and hemodynamic effects of thymulin administration in a rat model of monocrotaline (MCT)-induced PH, as well as the pattern of proinflammatory cytokine gen...