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Regulation of invasion and peritoneal dissemination of ovarian cancer by mesoth...

Coelho, R; Ricardo, S; Amaral, AL; Huang, YL; Nunes, M; Neves, JP; Mendes, N; López, MN; Bartosch, C; Ferreira, V; Portugal, R; Lopes, JM; Almeida, R

Peritoneal dissemination is a particular form of metastasis typically observed in ovarian cancer and the major cause for poor patient’s outcome. Identification of the molecular players involved in ovarian cancer dissemination can offer an approach to develop treatment strategies to improve clinical prognosis. Here, we identified mesothelin (MSLN) as a crucial protein in the multistep process of peritoneal disse...


Left ventricular pseudoaneurysm: a challenging diagnosis.

Faustino, M; Ranchordás, S; Abecasis, J; Freitas, A; Ferreira, M; Gil, V; Morais, C; Neves, JP

Left ventricular pseudoaneurysm is a rare complication of acute myocardial infarction, associated with high mortality. However, it can present in a non-specific manner, complicating and delaying the diagnosis. The authors present the case of a 65-year-old patient, hypertensive, with no other known relevant medical history, who presented with chest pain, cough and left pleural effusion, initially attributed to a...


Acute coronary syndrome of paradoxical origin

Ferreira, AR; Freitas, A; Magno, P; Soares, A; Abreu, PF; Neves, JP; Gil, VM

We describe a rare case of acute myocardial infarction secondary to paradoxical embolism complicating acute pulmonary embolism. A 44-year-old woman presented to the emergency department with chest pain. The physical examination was unremarkable except for oxygen saturation of 75%, and the electrocardiogram showed ST-segment elevation in the inferior leads. Urgent coronary angiography showed a distal occlusion o...


Understanding Cardiac Myxoma Recurrence: A Case Report

Carvalho, MS; Andrade, MJ; Abecasis, J; Gouveia, R; Branco, LM; Neves, JP; Mendes, M

Recurrence of cardiac myxoma is a rare condition, observed in about 3% of patients in sporadic cases, although it is more frequent in familial ones. Several mechanisms have been proposed to explain such recurrence, and the importance of increased vascularization as a facilitating feature is the subject of debate. The authors report the case of a non-familial right atrial myxoma, unusual for both its histopathol...


Primary Production and Nutrient Content in Two Salt Marsh

Neves, JP; Ferreira, LF; Simões, MP; Gazarini, LC

Seasonal variation patterns of aboveground and belowground biomass, net primary production, and nutrient accumulation were assessed in Atriplex portulacoides L. and Limoniastrum monopetalum (L.) Boiss. in Castro Marim salt marsh, Portugal. Sampling was conducted for five periods during 2001–2002 (autumn, winter, spring, summer, and autumn). This study indicates that both species have a clear seasonal variation ...


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