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Glycemic Control and Quality of Life Among People with Type 1 Diabetes: Relatio...
Dias, RJ; Neves, JS; Poínhos, RuiBackground/Objectives: Diabetes mellitus has physical, psychological and behavioral implications related to glycemic control and quality of life. Our aims were to evaluate glycemic control and disease-related quality of life among adults with type 1 diabetes mellitus and to study their relationships with sociodemographic, clinical and anthropometric characteristics. Methods: Eighty-five participants (49.4% fema...
Association of thyroid function, within the euthyroid range, with cardiovascula...
Neves, JS; Fontes-Carvalho, R; Borges-Canha, M; Leite, AR; von Hafe, M; Vale, C; Martins, S; Guimarães, JT; Carvalho, D; Leite-Moreira, A; Azevedo, ABackground: Thyroid hormones are important modulators of cardiovascular function. Both hypothyroidism and hyperthyroidism are known to contribute to an increased cardiovascular risk. It remains uncertain whether thyroid hormones level within the euthyroid range are associated with cardiometabolic risk. We aimed to evaluate the association between thyroid function levels within the euthyroid range and cardiovasc...
Oral glucose tolerance testing at 1 h and 2 h: relationship with glucose and ca...
Guerreiro, V; Maia, I; Neves, JS; Salazar, D; Ferreira, MJ; Mendonça, F; Silva, MM; Borges-Canha, M; Viana, S; Costa, C; Pedro, J; Varela, A; Lau, EBackground: One hour plasma glucose concentration (1hPG) during an oral glucose tolerance test (OGTT) may be an alternative to 2-h plasma glucose concentration (2hPG) in the identification of individuals at increased risk of hyperglycaemia, although its role is not fully understood. Aim: We aim to investigate the relationship of these measures with other glucose parameters, as well as their relationship with ca...
Thyroid Hormones within the Normal Range and Cardiac Function in the General Po...
Neves, JS; Fontes-Carvalho, R; Borges-Canha, M; Leite, AR; Martins, S; Oliveira, A; Guimarães, JT; Carvalho, D; Leite-Moreira, A; Azevedo, ABackground: Hypothyroidism and hyperthyroidism are associated with marked changes in cardiac structure and function. However, the association of thyroid function within the normal range with cardiac structure and function in the general population remains uncertain. Methods: Eight hundred thirty-five subjects aged ≥45 years from the EPIPorto cohort (evaluation between 2006 and 2008) were cross-sectionally analy...
The impact of vitamin d in non-alcoholic fatty liver disease: A cross-sectional...
Borges-Canha, M; Neves, JS; Mendonça, F; Silva, MM; Costa, C; Cabral, PM; Guerreiro, V; Lourenço, R; Meira, P; Salazar, D; Ferreira, MJ; Pedro, JPurpose: We aimed to evaluate the association between vitamin D status and hepatic function parameters and scores: Fatty Liver Index (FLI, predictor of hepatic steatosis) and BARD (BMI, AST/ALT ratio and DM, predictor of hepatic fibrosis) in patients with morbid obesity. Patients and Methods: Cross-sectional study including patients with morbid obesity followed in our centre between January 2010 and July 2018. ...
Beta Cell Function as a Baseline Predictor of Weight Loss After Bariatric Surgery
Borges-Canha, M; Neves, JS; Mendonça, F; Silva, MM; Costa, C; M Cabral, P; Guerreiro, V; Lourenço, R; Meira, P; Salazar, D; Ferreira, MJ; Pedro, JBackground: Obesity is a multifactorial disease, which is strongly associated to other metabolic disorders. Bariatric surgery is the most effective treatment of morbid obesity. The role of beta cell function in weight loss after bariatric surgery is uncertain. Aim: To evaluate the association between beta cell function and percentage of total body weight loss (TBWL%) 1, 2, 3, and 4 years after bariatric surgery...
Evaluation of thyroid function in patients hospitalized for acute heart failure
Leite, AR; Neves, JS; Borges-Canha, M; Vale, C; Von Hafe, M; Carvalho, D; Leite-Moreira, ABackground. Thyroid hormones (TH) are crucial for cardiovascular homeostasis. Recent evidence suggests that acute cardiovascular conditions, particularly acute heart failure (AHF), significantly impair the thyroid axis. Our aim was to evaluate the association of thyroid function with cardiovascular parameters and short-and long-term clinical outcomes in AHF patients. Methods. We performed a single-centre retros...
Adequate magnesium level as an associated factor of pre-diabetes and diabetes m...
Guerreiro, V; Maia, I; Neves, JS; Salazar, D; Ferreira, MJ; Mendonça, F; Silva, MM; Viana, S; Costa, C; Pedro, J; Varela, A; Lau, E; Freitas, PBariatric surgery (BS) can lead to remission of type 2 diabetes mellitus (T2DM), however, the evidence on the influence of preoperative serum magnesium levels on this reversal is scarce. To study the influence of preoperative serum magnesium levels on the pre-T2DM and T2DM remission one year after BS. Retrospective study carried out among 1656 patients with obesity who underwent BS in the Centro Hospitalar Univ...
Secondary Hyperparathyroidism Among Bariatric Patients: Unraveling the Prevalen...
Mendonça, FM; Neves, JS; Silva, MM; Borges Canha, M; Costa, C; Cabral, PM; Guerreiro, V; Lourenço, R; Meira, P; Correia, Flora; Salazar, D; Pedro, JIntroduction Bariatric surgery (BS) is the most effective therapeutic approach to obesity. It is associated with great gastrointestinal anatomic changes, predisposing the patients to altered nutrient absorption that impacts phosphocalcium metabolism. This study aimed to clarify the prevalence of secondary hyperparathyroidism (SHPT) and its predictors in patients submitted to BS. Methods Retrospective study of 1...
Impact of Bariatric Surgery on Long-term Cardiovascular Risk: Comparative Effec...
Oliveira, SC; Neves, JS; Souteiro, P; Pedro, J; Magalhães, D; Guerreiro, V; Bettencourt-Silva, R; Costa, MM; Varela, A; Barroso, I; Freitas, PIntroduction: Several reports highlight bariatric surgery as an efficient and long-lasting strategy for weight loss. Herein, we aimed to evaluate the impact of bariatric surgery on 10-year cardiovascular disease (CVD) risk and to compare the effectiveness of different surgical procedures, employing the Framingham Risk Score (FRS). Methods: Retrospective longitudinal observational study of patients undergoing ba...