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Improving health outcomes through treatment sequencing optimization in multiple...

Geraldes, C.; Neves, M.; Bergantim, R.; Silva, Catarina; Leal da Costa, F.

Objectives: Patients with multiple myeloma often require multiple treatment lines. The order in which treatments are sequenced has impact on clinical outcomes. This study aimed to estimate progression-free survival (PFS) and overall survival (OS) with common treatment sequences used in Portugal and the incremental benefit of an optimal sequence in transplant-ineligible patients with multiple myeloma. Methods: A...


Da lei à prática: contributo da intervenção precoce para o desenvolvimento das ...

Carvalho, O.; Neves, M.; Martins, R.; Pascoinho, J.; Galinha, Sónia Maria Gomes Alexandre

O estudo "Da Lei à Prática: Indicadores para a Inclusão", pretende apresentar os resultados da aplicação de um inquérito por questionário adaptado do “Índex para a Inclusão” de Booth e Ainscow (2002) em que se mediram um conjunto de indicadores para a inclusão. O inquérito foi aplicado no grupo “Espaço 54 – Grupo de Apoio à Educação Inclusiva” e responderam 155 elementos. O instrumento constitui um recurso para...


Depressive symptomatology, presenteeism productivity and quality of life

Lopes, S. L.; Ferreira, A. I.; Passos, A.; Neves, M.; Sousa, C.; Sá, M. J.

In this study we intend to test if presenteeism productivity influences the relationship between depressive symptoms and quality of life and also if this relation is conditional upon levels of information processing speed. Data were collected from 231 participants who completed a neuropsychological test and self-reported measures. Results revealed a significant indirect effect and a significant moderation effec...

Date: 2018   |   Origin: Repositório ISCTE

Meretoja's Syndrome: Lattice Corneal Dystrophy, Gelsolin Type

Casal, I.; Monteiro, S.; Abreu, C.; Neves, M.; Oliveira, L.; Beirão, João

Lattice corneal dystrophy gelsolin type was first described in 1969 by Jouko Meretoja, a Finnish ophthalmologist. It is caused by an autosomal dominant mutation in gelsolin gene resulting in unstable protein fragments and amyloid deposition in various organs. The age of onset is usually after the third decade of life and typical diagnostic triad includes progressive bilateral facial paralysis, loose skin, and l...


Methodology to assess medical processes based on a Failure Mode and Effects Ana...

Sobral, José; Teixeira, D.; Morais, H.; Neves, M.

Risk is always present in every activity and several methodologies are often used to reduce or mitigate situations where risk is unacceptable. Founded on this assumption, the present paper has the objective to propose a methodology to assess critical medical processes based on a Failure Mode and Effects Analysis (FMEA), identifying and making a hierarchy of the inherent activities belonging to those processes u...


A comparison of production control systems in a flexible flow shop

Silva, Cristóvão; Reis, V.; Morais, A.; Brilenkov, I.; Vaz, J.; Pinheiro, T.; Neves, M.; Henriques, M.; Varela, Leonilde; Pereira, G.

Production control in make-to-order must address the companies’ need for short delivery times and on-time deliveries. Several production control systems may be used to meet these needs. This paper presents a simulation study to evaluate the delivery performance of the TKS, GKS and POLCA production control systems, in the context of a make-to-order flexible flow shop. Since TKS is used for make-to-stock manufact...


A comparison of production control systems in a flexible flow shop

Silva, C.; Reis, V.; Morais, A.; Brilenkov, I.; Vaza, J.; Pinheiro, T.; Neves, M.; Henriques, M.; Varela, Maria Leonilde Rocha; Pereira, Guilherme

Production control in make-to-order must address the companies’ need for short delivery times and on-time deliveries. Several production control systems may be used to meet these needs. This paper presents a simulation study to evaluate the delivery performance of the TKS, GKS and POLCA production co ntrol systems, in the context of a make-to-order flexible flow shop. Since TKS is used for make-to-stock manufac...


Paralisia do plexo braquial – uma manifestação rara de infeção osteo-articular

Moutinho, A.; Valério, M.; Marques, I.; Carruscal, C.; Vieira, J.; Tavares, D.; Neves, M.

Introdução: A paralisia do plexo braquial é uma entidade rara após o período neonatal. Resulta habitualmente de mecanismos físicos, mas pode estar relacionada com infeções osteo- articulares. Há poucos casos descritos de associação entre estas infeções e a paralisia secundária a neuropatia. Na maioria dos casos a manifestação mais frequente é a pseudo-paralisia ou fraqueza aparente do membro afetado. Casos Clín...


BRBN-T validation: adaptation of the selective reminding test and word list gen...

Neves, M.; Passos, A. M.; Ferreira, A.; Sousa, C.; Sá, A.; Sá, M. J.

Objective: This study aims to present the Selective Reminding Test (SRI) and Word List Generation (WLG) adaptation to the Portuguese population, within the validation of the Brief Repeatable Battery of Neuropsychological Tests (BRBN-T) for multiple sclerosis .(MS) patients. Method: 66 healthy participants (54.5% female) recruited from the community volunteered to participate in this study. Results: A combinatio...

Date: 2015   |   Origin: Repositório ISCTE

Modelos de negócio e comunicação social: “telcos”, legacy media, novos media e ...

Cardoso, G.; Crespo, M.; Foa, C.; Lapa, T.; Quintanilha, Tiago Lima; Mendonça, S.; Moreno, J.; Neves, M.; Paisana, M.; Vieira, Jorge

Este não é um estudo “chave na mão” que solucione os problemas do sector da comunicação social portuguesa, do sector em outros países ou à escala global. O estudo é “apenas” um contributo para a identificação de tendências e de metodologias para reduzir a incerteza na gestão de empresas e redacções, procurando oferecer aquilo que, mais à frente, definimos enquanto uma “tecnologia de racionalidade”. É um estudo ...

Date: 2015   |   Origin: Repositório ISCTE

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