16 documents found, page 1 of 2

Is silver a precious metal for G-Quadruplex stabilization mediated by porphyrins?

Cancer is a leading cause of death, so continuous efforts into cancer therapy are imperative. In tumor cells, telomerase and oncogene activity are key points for uncontrolled cell growth. Targeting these processes with ligands that inhibit telomerase and/or reduce oncogene expression has been identified as a promising cancer therapy. This study evaluated the selectivity and affinity of the silverII complex of 5...

Wastewater disinfection with photodynamic treatment and evaluation of its ecoto...

Research has demonstrated the presence of viruses in wastewater (WW), which can remain viable for a long period, posing potential health risks. Conventional WW treatment methods involving UV light, chlorine and ozone efficiently reduce microbial concentrations, however, they produce hazardous byproducts and microbial resistance that are detrimental to human health and the ecosystem. Hence, there is a need for n...

Investigation of the potential of deep eutectic solvents (DES) as alternative s...

Antimicrobial Photodynamic Therapy (aPDT) is gaining recognition as an effective approach for the photoinactivation of a broad spectrum of microorganisms [1,2]. Due to their apolar behavior, photosensitizers (PS) often have low solubility in aqueous media requiring the use of toxic organic solvents that are incompatible with their application in the field [4]. In this study, the potential of Deep Eutectic Solve...

Deep Eutectic Solvents as alternative solvents in Antimicrobial Photodynamic Th...

A study of wastewater disinfection with photodynamic treatment and its ecotoxic...

A study of wastewater disinfection with photodynamic treatment and its ecotoxic...

Viruses have higher mutation rates when compared with other microorganisms, particularly RNA viruses [1]. The higher mutation rate promotes the development of resistance to traditional antivirals, establishing a resistance behavior in viruses populations [1]. RNA viruses in wastewater (WW) have already been reported, leading to potential public health risks [2]. Wastewater treated with conventional antimicrobia...

Starch-based films doped with porphyrinoid photosensitizers for active skin wou...

Starch is a biodegradable and biocompatible carbohydrate that, when combined with bioactive molecules, can be processed as biomimetic platforms with enhanced performance, allowing its use as active wound dressing materials. Porphyrinoid photosensitizers can tune the physicochemical/functional profile of biomacromolecules, allowing their use in anti-infective strategies. In this work, the feasibility of using th...

Starch-based films doped with porphyrinoid photosensitizers for active skin wou...

Starch is a biodegradable and biocompatible carbohydrate that, when combined with bioactive molecules, can be processed as biomimetic platforms with enhanced performance, allowing its use as active wound dressing materials. Porphyrinoid photosensitizers can tune the physicochemical/functional profile of biomacromolecules, allowing their use in anti-infective strategies. In this work, the feasibility of using th...

Disinfection of wastewater in the mitigation of SARS-CoV-2 by photodynamic trea...

Using aqueous solutions of ionic liquids as chlorophyll eluents in solid-phase ...

There is a need for handy and fast techniques to purify biomolecules, increasing their stability and value, because the separation units are current bottlenecks in downstream processes. Solid-phase extraction is a technique that enables the purification of a compound by its adsorption from a liquid matrix. The AmberLite™ HPR900 OH resin allows the separation of chlorophylls from complex extracts, however the re...