5 documents found, page 1 of 1
Photodynamic inactivation of phage Phi6 as SARS-CoV-2 model in wastewater disin...
Bartolomeu, Maria; Vieira, Cátia; Gomes, Marta; Gomes, Ana T. P. C.; Faustino, Maria Amparo F.; Neves, Maria Graça P. M. S.; Almeida, AdelaideThe past 2 years have been marked by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This virus is found in the intestinal tract and reaches the wastewater system, and, consequently, the natural receiving water bodies, and inappropriate or/and inefficient WW treatment is a means of contamination. In the present work, we used a SARS-CoV-2 model—the phage Phi6—to evaluate its survival u...
Photoinactivation of bacterial and fungal planktonic/biofilm forms using the co...
Vieira, Cátia; Bartolomeu, Maria; Santos, Adriele R.; Mesquita, Mariana Q.; Gomes, Ana T. P. C.; Neves, Maria Graça P. M. S.; Faustino, Maria Amparo F.Antimicrobial photodynamic therapy (aPDT) is a promising approach against multidrug-resistant microorganisms. In this work, we accessed the photodynamic efficiency of an affordable formulation composed of five cationic porphyrins (FORM) and its combined effect with potassium iodide (KI) on a large spectrum of microorganisms. For this purpose, the aPDT assays were conducted with FORM alone and FORM + KI on plank...
Photoinactivation of phage phi6 as a SARS-CoV-2 model in wastewater: evidence o...
Gomes, Marta; Bartolomeu, Maria; Vieira, Cátia; Gomes, Ana T. P. C.; Faustino, Maria Amparo F.; Neves, Maria Graça P. M. S.; Almeida, AdelaideThe last two years have been marked by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. This virus is found in the intestinal tract; it reaches wastewater systems and, consequently, the natural receiving water bodies. As such, inefficiently treated wastewater (WW) can be a means of contamination. The currently used methods for the disinfection of WW can lead to the formation of toxic c...
Photodynamic inactivation of mammalian viruses and bacteriophages
Costa, Liliana; Faustino, Maria Amparo F.; Neves, Maria Graça P. M. S.; Cunha, Ângela; Almeida, AdelaidePhotodynamic inactivation (PDI) has been used to inactivate microorganisms through the use of photosensitizers. The inactivation of mammalian viruses and bacteriophages by photosensitization has been applied with success since the first decades of the last century. Due to the fact that mammalian viruses are known to pose a threat to public health and that bacteriophages are frequently used as models of mammalia...
Bioluminescence and its application in the monitoring of antimicrobial photodyn...
Alves, Eliana; Costa, Liliana; Cunha, Ângela; Faustino, Maria Amparo F.; Neves, Maria Graça P. M. S.; Almeida, AdelaideLight output from bioluminescent microorganisms is a highly sensitive reporter of their metabolic activity and therefore can be used to monitor in real time the effects of antimicrobials. Antimicrobial photodynamic therapy (aPDT) is receiving considerable attention for its potentialities as a new antimicrobial treatment modality. This therapy combines oxygen, a nontoxic photoactive photosensitizer, and visible ...