17 documents found, page 1 of 2

Etanercept in the treatment of ankylosing spondylitis and nephrotic syndrome in...

Dear Editor, Amyloidosis represents a family of diseases characterized by the deposition of proteinaceous material in the extracellular space that, by forming insoluble clusters on various tissues and organs, affects its function.

Peritoneal Dialysis in the Current Pandemic Crisis: An Opportunity for Reflection

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A diálise peritoneal na actual crise pandémica: uma oportunidade de reflexão

São difíceis os tempos que se vivem, e tempos mais difíceis poderão estar por chegar. A actual pandemia do novo coronavírus obrigou a uma total reformulação da sociedade em geral e, em especial, dos cuidados que concernem à área da saúde.

FGF23-klotho axis as predictive factors of fractures in type 2 diabetics with e...

Background: The aim of our study was to evaluate the relevance of FGF23-klotho axis in the predisposition for bone fractures in type 2 diabetic patients with early chronic kidney disease. Methods: In a prospective study we included 126 type 2 diabetic patients with CKD stages 2-3 (from 2010 to 2017). We used descriptive statistics, ANOVA and chi-square test. Our population was divided into two groups according ...

Gla-rich protein (GRP) as an early and novel marker of vascular calcification a...

Vascular calcification (VC) is one of the strongest predictors of cardiovascular risk in chronic kidney disease (CKD) patients. New diagnostic/prognostic tools are required for early detection of VC allowing interventional strategies. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor, whose clinical utility is here highlighted. The present study explores, for the first time, correlations betwee...

Resistin as a predictor of cardiovascular hospital admissions and renal deterio...

Background: High resistin levels have been associated with cardiovascular disease (CVD). Cardiovascular hospitalizations are common, especially in diabetic and renal impaired patients. The purpose of this study is to determine the role of serum resistin as a predictor of cardiovascular hospitalizations in type 2 diabetic patients with mild to moderate chronic kidney disease (CKD). Methods: We conducted a prospe...

One-year rehospitalisations for congestive heart failure in Portuguese NHS hosp...

Identification of rehospitalisations for heart failure and contributing factors flags health policy intervention opportunities designed to deliver care at a most effective and efficient level. Recognising that heart failure is a condition for which timely and appropriate outpatient care can potentially prevent the use of inpatient services, we aimed to determine to what extent comorbidities and material depriva...

Plasmatic Klotho and FGF23 levels as biomarkers of CKD-associated cardiac disea...

Research over the past decade has focused on the role of Klotho as a cardio protective agent that prevents the effects of aging on the heart and reduces the burden of cardiovascular disease CVD. The role of the interaction between fibroblast growth factor 23-(FGF-23)/Klotho in Klotho-mediated actions is still under debate. The main objective was to ascertain the potential use of plasmatic Klotho and FGF23 as ma...

Klotho levels: association with insulin resistance and albumin-to-creatinine ra...

The present study aimed at evaluating the relationship between Klotho levels and insulin resistance and albumin-to-creatinine ratio (ACR) in type 2 diabetic patients with CKD. We conducted an observational, cross-sectional study in our outpatient diabetic nephropathy clinic from 2014 to 2016, enrolling a total of 107 type 2 diabetic patients with stage 2-3 CKD, with a mean age of 59 years. Several clinical and ...

Pseudomonas mendocina: the first case of peritonitis on peritoneal dialysis