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Open-Air Cold Plasma Device Leads to Selective Tumor Cell Cytotoxicity

Almeida-Ferreira, Catarina; Silva-Teixeira, Rafael; Laranjo, Mafalda; Almeida, Nuno; Brites, Gonçalo; Dias-Ferreira, João; Marques, Inês A.; Neves, Rita

The need for effective and safe therapies for cancer is growing as aging is modifying its epidemiology. Cold atmospheric plasma (CAP) has gained attention as a potential anti-tumor therapy. CAP is a gas with enough energy to ionize a significant fraction of its constituent particles, forming equal numbers of positive ions and electrons. Timely-resolved output voltage measurement, emission spectroscopy, and quan...



Diabetes mellitus and prostate cancer metabolism: Is there a relationship?

Antunes, Hugo Pontes; Teixo, Ricardo; Carvalho, João André; Eliseu, Miguel; Marques, Inês; Mamede, Ana; Neves, Rita; Oliveira, Rui

Objective: Our aim was to evaluate the effects of glucose levels and diabetes mellitus in prostate cancer (PCa) biology. Materials and methods: Two PCa cell lines (LNCap and PC3) were cultured in RPMI medium with different glucose concentrations [5mM (LG) and 25mM (HG)]. Expressions of androgen receptor, Her2/neu and glucose transporters (GLUT1, 3, 5 and 12) were evaluated by flow cytometry. Proliferation rate ...


Os Agentes Termofísicos

Neves, Rita; Rosado, Maria da Lapa

Problema: A utilização inadequada e/ou a falta de padrões de prática das modalidades termofísicas em Portugal, motivou a elaboração de um documento, um levantamento de informação, objectiva, em que qualquer fisioterapeuta se possa alicerçar para aplicar estas modalidades com o máximo rigor e seguindo todos os padrões de prática, garantindo assim a segurança dos utentes e do fisioterapeuta. Objectivo: Contribuir...


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