2 documents found, page 1 of 1
Peptides ToAP3 and ToAP4 decrease release of inflammatory cytokines through TLR...
Veloso Júnior, Paulo Henrique de Holanda; Simon, Karina Smidt; Castro, Raffael Júnio Araújo de; Coelho, Luísa Coutinho; Hurtado Erazo, Fabián AndresAntimicrobial peptides (AMPs) are small molecules with microbicidal and immunoregulatory activities. In this study we evaluated the anti-inflammatory and antimicrobial activities of peptides ToAP3 and ToAP4, AMPs from the venom of the Brazilian scorpion Tityus obscurus. To test the peptides’ activity, murine bone marrow-derived macrophages (BMDMs) or dendritic cells (BMDCs) were stimulated with peptides plus LP...
Non-disulfide-Bridge peptide 5.5 from the Scorpion Hadrurus gertschi Inhibits t...
Trentini, Monalisa Martins; Neves, Rogério Coutinho das; Santos, Bruno de Paula Oliveira; Silva, Roosevelt Alves da; Souza, Adolfo CarlosMulti-drug resistant microorganisms have been a growing concern during the last decades due to their contribution in mortality rates worldwide. Antimicrobial peptides (AMPs) are broad spectrum antimicrobial agents that display potent microbicidal activity against a wide range of microorganisms. AMPs generally have a rapid mode of action that reduces the risk of resistance developing among pathogens. In this stu...