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Nitric oxide-mediated immune complex-induced prostaglandin E2 production by per...

Neves, Simone M. F.; Rezende, Simone Aparecida; Goes, Alfredo Miranda de

Granuloma reaction around Schistosoma mansoni eggs is the prominent lesion in human schistosomiasis. Studies have suggested the involvement of a series of suppressive mechanisms in the control of this reaction. Using an in vitro model of granuloma formation, we have shown that immune complexes (IC) isolated from sera of chronic intestinal schistosomiasis patients were able to reduce granulomatous reaction devel...

Date: 2014   |   Origin: Oasisbr
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