Funding Information: Project partially supported by Harvard Medical School \u2013 Portugal Program ( HMSPICJ/0022/2011 ), Instituto Nacional de Sa\u00FAde Dr. Ricardo Jorge \u2013 INSA, Centro de Toxicogen\u00F3mica e Sa\u00FAde Humana \u2013 ToxOmics, Rede Nacional de Espectrometria de Massa \u2013 RNEM, FCT /Poly-Annual Funding Program and FEDER /Sa\u00FAde XXI Program, Portugal. Cristina Coelho (SFRH/BD/1335...
Obstructive Sleep Apnea (OSA) is characterized by recurrent-episodes of apneas/hypopneas during sleep, leading to recurrent intermittent-hypoxia and sleep fragmentation. Non-treated OSA can result in cardiometabolic diseases. In this study, we applied a shotgun-proteomics strategy to deeper investigate the red blood cell-(RBC) homeostasis regulation in the context of OSA-severity and their response to six month...
Funding Information: This work was supported by the Calouste Gulbenkian Foundation, Rede Nacional de Espectrometria de Massa (RNEM), National Institute of Health Doctor Ricardo Jorge, and UID/04923 - Comprehensive Health Research Centre.Sofia Neves (SFRH/BD/82648/2011), Solange A. Pacheco (SFRH/BD/74857/2010), Cristina Valentim-Coelho (SFRH/BD/133511/2017) and Joana Saraiva (2022.14435.BD) were granted with PhD...
Research shows lesbian, gay, bisexual, trans and intersex (LGBTI) people are vulnerable to more adverse childhood experiences (ACEs). The research focused on the perceptions of experiencing ACEs among 36 Portuguese LGBTI people who were exposed to domestic violence by their parents or other family members (M = 34.11; SD = 10.77). Semi-structured individual interviews were conducted and data were subjected to th...
As Portugal lived under a dictatorship for almost 50 years, policies and legislation on women’s rights began to be developed only after the instauration of democracy in 1975 (Monteiro and Ferreira, 2016). In the second half of the 20th century, especially after the feminist movement gained strength, broader discussions about sexual harassment (SH) in Portugal began to emerge. A greater awareness of SH as a form...
O presente texto tem como objetivo apresentar uma breve reflexão crítica sobre a proteção que tem sido dada às mulheres vítimas de violência doméstica, em Portugal, nas últimas décadas, salientando alguns avanços legislativos e em matéria de políticas públicas. Discute-se a importância de enquadrar a violência doméstica no contexto da violência de género, em consonância com a Convenção de Istambul, e de adotar ...
Os não-fumadores expostos ao fumo do cigarro passivo ou, simplesmente fumo passivo (FP), apresentam um risco acrescido de desenvolver diversas doenças graves. No entanto, os mecanismos moleculares que explicam estes efeitos continuam pouco esclarecidos, o que reforça a necessidade de identificar biomarcadores capazes de avaliar o risco associado a esta exposição. Neste estudo, analisámos o proteoma do epitélio ...
Bullying and cyberbullying significantly threaten the development and mental health of both victims and perpetrators. This study aimed to analyze the associations between socioeconomic characteristics, personal experiences of violence, perceived social support from peers, and acceptance of violence and (cyber)bullying perpetration. The study involved 1146 secondary school students, consisting of 698 females and...
Non-smokers exposed to second-hand smoke (SHS) present risk of developing tobacco smoke-associated pathologies. To investigate the airway molecular response to SHS exposure that could be used in health risk assessment, comparative shotgun proteomics was performed on nasal epithelium from a group of healthy restaurant workers, non-smokers (never and former) exposed and not exposed to SHS in the workplace. HIF1α-...
Bullying and cyberbullying significantly threaten the development and mental health of both victims and perpetrators. This study aimed to analyze the associations between socioeconomic characteristics, personal experiences of violence, perceived social support from peers, and acceptance of violence and (cyber)bullying perpetration. The study involved 1146 secondary school students, consisting of 698 females and...