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DNA methyltransferase expression (DNMT1, DNMT3a, and DNMT3b) as a potential bio...

Camacho, Pedro; Ribeiro, Edna; Pereira, Bruno; Nascimento, João; Rosa, Paulo Caldeira; Henriques, José; Barrão, Sandra; Sadio, Silvia; Quendera, Bruno

Background/Objectives: Age-related macular degeneration (AMD) is a global cause of vision loss, with limited therapeutic options highlighting the need for effective biomarkers. This study aimed to characterize plasma DNA methyltransferase expression (DNMT1, DNMT3A, and DNMT3B) in AMD patients and explore divergent expression patterns across different stages of AMD. Methods: Thirty-eight AMD patients were prospe...

Date: 2025   |   Origin: Repositório Científico do Instituto Politécnico de Lisboa
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