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Unveiling the Cost-Effectiveness of Chlamydia Screening Strategies: A Systemati...

Mata, E; Angélico-Gonçalves, A; Leite, AR; Queiroz Almeida, D

Background: Cost-effectiveness analyses of preventive screening strategies are paramount for public health to ensure effective resource use, especially for sexually transmitted infections such as Chlamydia, which lead to significant quality-adjusted life years (QALY) loss. Summary: This study systematically reviewed EMBASE, PubMed, and SCOPUS databases, from inception to October 2022, Chlamydia infection screen...


Association of thyroid function, within the euthyroid range, with cardiovascula...

Neves, JS; Fontes-Carvalho, R; Borges-Canha, M; Leite, AR; von Hafe, M; Vale, C; Martins, S; Guimarães, JT; Carvalho, D; Leite-Moreira, A; Azevedo, A

Background: Thyroid hormones are important modulators of cardiovascular function. Both hypothyroidism and hyperthyroidism are known to contribute to an increased cardiovascular risk. It remains uncertain whether thyroid hormones level within the euthyroid range are associated with cardiometabolic risk. We aimed to evaluate the association between thyroid function levels within the euthyroid range and cardiovasc...


Thyroid Hormones within the Normal Range and Cardiac Function in the General Po...

Neves, JS; Fontes-Carvalho, R; Borges-Canha, M; Leite, AR; Martins, S; Oliveira, A; Guimarães, JT; Carvalho, D; Leite-Moreira, A; Azevedo, A

Background: Hypothyroidism and hyperthyroidism are associated with marked changes in cardiac structure and function. However, the association of thyroid function within the normal range with cardiac structure and function in the general population remains uncertain. Methods: Eight hundred thirty-five subjects aged ≥45 years from the EPIPorto cohort (evaluation between 2006 and 2008) were cross-sectionally analy...


The impact of vitamin d in non-alcoholic fatty liver disease: A cross-sectional...

Borges-Canha, M; Neves, JS; Mendonça, F; Silva, MM; Costa, C; Cabral, PM; Guerreiro, V; Lourenço, R; Meira, P; Salazar, D; Ferreira, MJ; Pedro, J

Purpose: We aimed to evaluate the association between vitamin D status and hepatic function parameters and scores: Fatty Liver Index (FLI, predictor of hepatic steatosis) and BARD (BMI, AST/ALT ratio and DM, predictor of hepatic fibrosis) in patients with morbid obesity. Patients and Methods: Cross-sectional study including patients with morbid obesity followed in our centre between January 2010 and July 2018. ...


Evaluation of thyroid function in patients hospitalized for acute heart failure

Leite, AR; Neves, JS; Borges-Canha, M; Vale, C; Von Hafe, M; Carvalho, D; Leite-Moreira, A

Background. Thyroid hormones (TH) are crucial for cardiovascular homeostasis. Recent evidence suggests that acute cardiovascular conditions, particularly acute heart failure (AHF), significantly impair the thyroid axis. Our aim was to evaluate the association of thyroid function with cardiovascular parameters and short-and long-term clinical outcomes in AHF patients. Methods. We performed a single-centre retros...


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