2 documents found, page 1 of 1
Balancing access to BPaLM regimens and risk of resistance
Van Rie, Annelies; Walker, Timothy; de Jong, Bouke; Rupasinghe, Praharshinie; Rivière, Emmanuel; Dartois, Véronique; Sonnenkalb, Lindsay; Machado, DianaFunding Information: AVR reports receiving funding from Research Foundation Flanders (Belgium) related to whole-genome sequencing of M tuberculosis. BdJ reports an institutional contract for central laboratory support to the C211 pediatric bedaquiline trial with Janssen and participation in the scientific advisory boards of the Dioraphte foundation and Panacea. PS reports personal consulting fees from Genoscree...
Ancient and recent differences in the intrinsic susceptibility of Mycobacterium...
Bateson, Anna; Canseco, Julio Ortiz; McHugh, Timothy D.; Witney, Adam A.; Feuerriegel, Silke; Merker, Matthias; Kohl, Thomas A.; Utpatel, ChristianObjectives: To develop a robust phenotypic antimicrobial susceptibility testing (AST) method with a correctly set breakpoint for pretomanid (Pa), the most recently approved anti-tuberculosis drug. Methods: The Becton Dickinson Mycobacterial Growth Indicator Tube™ (MGIT) system was used at six laboratories to determine the MICs of a phylogenetically diverse collection of 356 Mycobacterium tuberculosis complex (M...