A 39-year-old male with a recent diagnosis of human immunodeficiency virus infection, in the AIDS stage, and Burkitt lymphoma, both identified in the context of a constitutional syndrome with six months of evolution developed an acute condition with psychomotor slowing, disorientation, and gait imbalance, six weeks after initiating antiretroviral therapy and chemotherapy. Neurological examination revealed multi...
Introduction: Psychiatric comorbidities have a significant impact on patients’ quality of life and often go undetected in neurologic practice. The aim of this study was to describe and characterize psychiatric comorbidities among patients hospitalized due to a neurologic disorder in mainland Portugal.Methods: A retrospective observational study was performed by analyzing hospitalization with a primary diagnosis...
Pico Island is one of the islands of the Azores archipelago located in the North Atlantic Ocean, where there are very specific conditions for vine cultivation. In this context, there is scarce knowledge related to grape ripening under these conditions. Thus, the aim of this study was to evaluate several physicochemical parameters, the phenolic composition, antioxidant capacity, and varietal aromatic potential, ...
Endophytic fungi are promising producers of phenolic compounds; however, the process of extracting these molecules from the culture medium is a crucial step for obtaining these metabolites. In this context, the best conditions for extracting phenolic compounds produced by Cophinforma mamane CF2-13, isolated from an Amazonian plant, were evaluated. The fungus was cultivated in a liquid medium to obtain its metab...
This clinical guideline was designed to serve as a hospital guide in the diagnostic, therapeutic, and monitoring approach to neurosyphilis, considering whether there is positivity or not for the human immunodeficiency virus. Syphilis is a sexually transmitted notifiable disease, known as the great imitator. In around 30% of cases of untreated disease, there is a persistent central nervous system infection. Neur...
Arterial dissection is an uncommon complication of reversible cerebral vasoconstriction syndrome (RCVS). We describe the case of a 35-year-old woman with a migraine history who presented with recurrent thunderclap headache and focal neurological signs, including right hemiataxia. She had been diagnosed with COVID-19 disease two weeks earlier. Neuroimaging revealed multifocal stenosis of the posterior circulatio...
Introduction: Promoting health literacy is essential for patients to make informed healthcare decisions, ensuring more efficient resource utilization and contributing to long-term sustainability. Objectives: Enhance health literacy among patients in six health units in Northern Portugal, focusing on the organization and structure of primary healthcare services (PHC) and the medical specialty of general practice...
Introduction: Polymedication is defined by the simultaneous use, appropriate or not, according to the comorbidities of each patient, of at least five drugs in the same person. The family physician (FP) should identify and combat, when clinically appropriate, polypharmacy. Objectives: To identify the prevalence of polymedication and the main potentially inappropriate pharmacological classes used in the elderly p...
Analisamos a relação entre desenvolvimento motor e dimensões do brincar em crianças pequenas, recorrendo a um questionário fechado sobre marcos motores na 1ª infância, padrão de brincar, coordenação motora, e estatuto socioeconómico, preenchido por mães/pais, entre março e abril de 2021, de 28 crianças (3,89±,88 anos de idade, 14 meninas). Foram detetadas 3 crianças com provável problema de desenvolvimento da c...