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Altered plasma protein profiles in genetic FTD – a GENFI study

Ullgren, Abbe; Öijerstedt, Linn; Olofsson, Jennie; Bergström, Sofia; Remnestål, Julia; van Swieten, John C.; Jiskoot, Lize C.; Seelaar, Harro

Background: Plasma biomarkers reflecting the pathology of frontotemporal dementia would add significant value to clinical practice, to the design and implementation of treatment trials as well as our understanding of disease mechanisms. The aim of this study was to explore the levels of multiple plasma proteins in individuals from families with genetic frontotemporal dementia. Methods: Blood samples from 693 pa...


Arterial stiffness and influences of the metabolic syndrome: a cross-countries ...

Scuteri, Angelo; Cunha, Pedro Guimarães; Rosei, E. Agabiti; Bekaert, Sofie; Cockcrofti, John R.; Cotter, Jorge; Cucca, Francesco; De Buyzere, Marc L.

Specific clusters of metabolic syndrome (MetS) components impact differentially on arterial stiffness, indexed as pulse wave velocity (PWV). Of note, in several population-based studies participating in the MARE (Metabolic syndrome and Arteries REsearch) Consortium the occurrence of specific clusters of MetS differed markedly across Europe and the US. The aim of the present study was to investigate whether spec...


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